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Autocrine-based selection of ligands for personalized CAR-T therapy of lymphoma.
Stepanov AV, Markov OV, Chernikov IV, Gladkikh DV, Zhang H, Jones T, Sen'kova AV, Chernolovskaya EL, Zenkova MA, Kalinin RS, Rubtsova MP, Meleshko AN, Genkin DD, Belogurov AA Jr, Xie J, Gabibov AG, Lerner RA. Stepanov AV, et al. Among authors: lerner ra. Sci Adv. 2018 Nov 14;4(11):eaau4580. doi: 10.1126/sciadv.aau4580. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30443597 Free PMC article.
Antigen-Specific Stimulation and Expansion of CAR-T Cells Using Membrane Vesicles as Target Cell Surrogates.
Ukrainskaya V, Rubtsov Y, Pershin D, Podoplelova N, Terekhov S, Yaroshevich I, Sokolova A, Bagrov D, Kulakovskaya E, Shipunova V, Deyev S, Ziganshin R, Chernov A, Telegin G, Maksimov E, Markov O, Oshchepkova A, Zenkova M, Xie J, Zhang H, Gabibov A, Maschan M, Stepanov A, Lerner R. Ukrainskaya V, et al. Small. 2021 Nov;17(45):e2102643. doi: 10.1002/smll.202102643. Epub 2021 Oct 3. Small. 2021. PMID: 34605165
Robotic QM/MM-driven maturation of antibody combining sites.
Smirnov IV, Golovin AV, Chatziefthimiou SD, Stepanova AV, Peng Y, Zolotareva OI, Belogurov AA Jr, Kurkova IN, Ponomarenko NA, Wilmanns M, Blackburn GM, Gabibov AG, Lerner RA. Smirnov IV, et al. Among authors: lerner ra. Sci Adv. 2016 Oct 19;2(10):e1501695. doi: 10.1126/sciadv.1501695. eCollection 2016 Oct. Sci Adv. 2016. PMID: 27774510 Free PMC article.
Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library.
Merkouris S, Barde YA, Binley KE, Allen ND, Stepanov AV, Wu NC, Grande G, Lin CW, Li M, Nan X, Chacon-Fernandez P, DiStefano PS, Lindsay RM, Lerner RA, Xie J. Merkouris S, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7023-E7032. doi: 10.1073/pnas.1806660115. Epub 2018 Jul 9. Proc Natl Acad Sci U S A. 2018. PMID: 29987039 Free PMC article.
395 results