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Oral digoxin effects on exercise performance, K+ regulation and skeletal muscle Na+ ,K+ -ATPase in healthy humans.
J Physiol. 2022 Aug;600(16):3749-3774. doi: 10.1113/JP283017. Epub 2022 Aug 2.
J Physiol. 2022.
PMID: 35837833
Free PMC article.
Clinical Trial.
Prolonged exercise to fatigue in humans impairs skeletal muscle Na+-K+-ATPase activity, sarcoplasmic reticulum Ca2+ release, and Ca2+ uptake.
Leppik JA, Aughey RJ, Medved I, Fairweather I, Carey MF, McKenna MJ.
Leppik JA, et al.
J Appl Physiol (1985). 2004 Oct;97(4):1414-23. doi: 10.1152/japplphysiol.00964.2003. Epub 2004 May 21.
J Appl Physiol (1985). 2004.
PMID: 15155714
Free article.
Clinical Trial.
Item in Clipboard
Intense exercise up-regulates Na+,K+-ATPase isoform mRNA, but not protein expression in human skeletal muscle.
Murphy KT, Snow RJ, Petersen AC, Murphy RM, Mollica J, Lee JS, Garnham AP, Aughey RJ, Leppik JA, Medved I, Cameron-Smith D, McKenna MJ.
Murphy KT, et al. Among authors: leppik ja.
J Physiol. 2004 Apr 15;556(Pt 2):507-19. doi: 10.1113/jphysiol.2003.054981. Epub 2004 Jan 30.
J Physiol. 2004.
PMID: 14754991
Free PMC article.
Item in Clipboard
Depressed Na+-K+-ATPase activity in skeletal muscle at fatigue is correlated with increased Na+-K+-ATPase mRNA expression following intense exercise.
Petersen AC, Murphy KT, Snow RJ, Leppik JA, Aughey RJ, Garnham AP, Cameron-Smith D, McKenna MJ.
Petersen AC, et al. Among authors: leppik ja.
Am J Physiol Regul Integr Comp Physiol. 2005 Jul;289(1):R266-74. doi: 10.1152/ajpregu.00378.2004. Epub 2005 Mar 24.
Am J Physiol Regul Integr Comp Physiol. 2005.
PMID: 15790751
Free article.
Item in Clipboard
Prolonged submaximal exercise induces isoform-specific Na+-K+-ATPase mRNA and protein responses in human skeletal muscle.
Murphy KT, Petersen AC, Goodman C, Gong X, Leppik JA, Garnham AP, Cameron-Smith D, Snow RJ, McKenna MJ.
Murphy KT, et al. Among authors: leppik ja.
Am J Physiol Regul Integr Comp Physiol. 2006 Feb;290(2):R414-24. doi: 10.1152/ajpregu.00172.2005. Epub 2005 Sep 22.
Am J Physiol Regul Integr Comp Physiol. 2006.
PMID: 16179492
Free article.
Clinical Trial.
Item in Clipboard
Exercise performance falls over time in patients with chronic kidney disease despite maintenance of hemoglobin concentration.
Leikis MJ, McKenna MJ, Petersen AC, Kent AB, Murphy KT, Leppik JA, Gong X, McMahon LP.
Leikis MJ, et al. Among authors: leppik ja.
Clin J Am Soc Nephrol. 2006 May;1(3):488-95. doi: 10.2215/CJN.01501005. Epub 2006 Apr 19.
Clin J Am Soc Nephrol. 2006.
PMID: 17699250
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N-acetylcysteine infusion alters blood redox status but not time to fatigue during intense exercise in humans.
Medved I, Brown MJ, Bjorksten AR, Leppik JA, Sostaric S, McKenna MJ.
Medved I, et al. Among authors: leppik ja.
J Appl Physiol (1985). 2003 Apr;94(4):1572-82. doi: 10.1152/japplphysiol.00884.2002. Epub 2002 Dec 20.
J Appl Physiol (1985). 2003.
PMID: 12496140
Free article.
Clinical Trial.
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