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Expression of the monocarboxylate transporter MCT1 is required for virus-specific mouse CD8+ T cell memory development.
Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2306763121. doi: 10.1073/pnas.2306763121. Epub 2024 Mar 18.
Proc Natl Acad Sci U S A. 2024.
PMID: 38498711
Free PMC article.
Reductive carboxylation epigenetically instructs T cell differentiation.
Jaccard A, Wyss T, Maldonado-Pérez N, Rath JA, Bevilacqua A, Peng JJ, Lepez A, Von Gunten C, Franco F, Kao KC, Camviel N, Martín F, Ghesquière B, Migliorini D, Arber C, Romero P, Ho PC, Wenes M.
Jaccard A, et al. Among authors: lepez a.
Nature. 2023 Sep;621(7980):849-856. doi: 10.1038/s41586-023-06546-y. Epub 2023 Sep 20.
Nature. 2023.
PMID: 37730993
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The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function.
Wenes M, Jaccard A, Wyss T, Maldonado-Pérez N, Teoh ST, Lepez A, Renaud F, Franco F, Waridel P, Yacoub Maroun C, Tschumi B, Dumauthioz N, Zhang L, Donda A, Martín F, Migliorini D, Lunt SY, Ho PC, Romero P.
Wenes M, et al. Among authors: lepez a.
Cell Metab. 2022 May 3;34(5):731-746.e9. doi: 10.1016/j.cmet.2022.03.013. Epub 2022 Apr 21.
Cell Metab. 2022.
PMID: 35452600
Free PMC article.
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Long-term T cell fitness and proliferation is driven by AMPK-dependent regulation of reactive oxygen species.
Lepez A, Pirnay T, Denanglaire S, Perez-Morga D, Vermeersch M, Leo O, Andris F.
Lepez A, et al.
Sci Rep. 2020 Dec 10;10(1):21673. doi: 10.1038/s41598-020-78715-2.
Sci Rep. 2020.
PMID: 33303820
Free PMC article.
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