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Prefrontal cortex astroglia modulate anhedonia-like behavior.
Codeluppi SA, Xu M, Bansal Y, Lepack AE, Duric V, Chow M, Muir J, Bagot RC, Licznerski P, Wilber SL, Sanacora G, Sibille E, Duman RS, Pittenger C, Banasr M. Codeluppi SA, et al. Among authors: lepack ae. Mol Psychiatry. 2023 Nov;28(11):4632-4641. doi: 10.1038/s41380-023-02246-1. Epub 2023 Sep 11. Mol Psychiatry. 2023. PMID: 37696873 Free PMC article.
Prefrontal Cortex Astroglia Modulate Anhedonia-like Behavior.
Codeluppi SA, Xu M, Bansal Y, Lepack AE, Duric V, Chow M, Muir J, Bagot RC, Licznerski P, Wilber SL, Sanacora G, Sibille E, Duman RS, Pittenger C, Banasr M. Codeluppi SA, et al. Among authors: lepack ae. Res Sq [Preprint]. 2023 Jun 30:rs.3.rs-3093428. doi: 10.21203/rs.3.rs-3093428/v1. Res Sq. 2023. PMID: 37461693 Free PMC article. Updated. Preprint.
Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior.
Al-Kachak A, Fulton SL, Di Salvo G, Chan JC, Farrelly LA, Lepack AE, Bastle RM, Kong L, Cathomas F, Newman EL, Menard C, Ramakrishnan A, Safovich P, Lyu Y, Covington HE 3rd, Shen L, Gleason K, Tamminga CA, Russo SJ, Maze I. Al-Kachak A, et al. Among authors: lepack ae. bioRxiv [Preprint]. 2023 Sep 16:2023.05.04.539464. doi: 10.1101/2023.05.04.539464. bioRxiv. 2023. PMID: 37205414 Free PMC article. Preprint.
ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex.
Fulton SL, Bendl J, Gameiro-Ros I, Fullard JF, Al-Kachak A, Lepack AE, Stewart AF, Singh S, Poller WC, Bastle RM, Hauberg ME, Fakira AK, Chen M, Cuttoli RD, Cathomas F, Ramakrishnan A, Gleason K, Shen L, Tamminga CA, Milosevic A, Russo SJ, Swirski F, Blitzer RD, Slesinger PA, Roussos P, Maze I. Fulton SL, et al. Among authors: lepack ae. bioRxiv [Preprint]. 2023 May 4:2023.05.04.539425. doi: 10.1101/2023.05.04.539425. bioRxiv. 2023. PMID: 37205394 Free PMC article. Preprint.
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.
Fulton SL, Wenderski W, Lepack AE, Eagle AL, Fanutza T, Bastle RM, Ramakrishnan A, Hays EC, Neal A, Bendl J, Farrelly LA, Al-Kachak A, Lyu Y, Cetin B, Chan JC, Tran TN, Neve RL, Roper RJ, Brennand KJ, Roussos P, Schimenti JC, Friedman AK, Shen L, Blitzer RD, Robison AJ, Crabtree GR, Maze I. Fulton SL, et al. Among authors: lepack ae. Nat Commun. 2022 Oct 26;13(1):6384. doi: 10.1038/s41467-022-34200-0. Nat Commun. 2022. PMID: 36289231 Free PMC article.
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking.
Lepack AE, Werner CT, Stewart AF, Fulton SL, Zhong P, Farrelly LA, Smith ACW, Ramakrishnan A, Lyu Y, Bastle RM, Martin JA, Mitra S, O'Connor RM, Wang ZJ, Molina H, Turecki G, Shen L, Yan Z, Calipari ES, Dietz DM, Kenny PJ, Maze I. Lepack AE, et al. Science. 2020 Apr 10;368(6487):197-201. doi: 10.1126/science.aaw8806. Science. 2020. PMID: 32273471 Free PMC article.
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex.
Lorsch ZS, Hamilton PJ, Ramakrishnan A, Parise EM, Salery M, Wright WJ, Lepack AE, Mews P, Issler O, McKenzie A, Zhou X, Parise LF, Pirpinias ST, Ortiz Torres I, Kronman HG, Montgomery SE, Loh YE, Labonté B, Conkey A, Symonds AE, Neve RL, Turecki G, Maze I, Dong Y, Zhang B, Shen L, Bagot RC, Nestler EJ. Lorsch ZS, et al. Among authors: lepack ae. Nat Neurosci. 2019 Sep;22(9):1413-1423. doi: 10.1038/s41593-019-0462-8. Epub 2019 Aug 19. Nat Neurosci. 2019. PMID: 31427770 Free PMC article.
21 results