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BTK inhibitors synergise with 5-FU to treat drug-resistant TP53-null colon cancers.
Lavitrano M, Ianzano L, Bonomo S, Cialdella A, Cerrito MG, Pisano F, Missaglia C, Giovannoni R, Romano G, McLean CM, Voest EE, D'Amato F, Noli B, Ferri GL, Agostini M, Pucciarelli S, Helin K, Leone BE, Canzonieri V, Grassilli E. Lavitrano M, et al. Among authors: leone be. J Pathol. 2020 Feb;250(2):134-147. doi: 10.1002/path.5347. Epub 2019 Dec 2. J Pathol. 2020. PMID: 31518438
Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy.
Grassilli E, Narloch R, Federzoni E, Ianzano L, Pisano F, Giovannoni R, Romano G, Masiero L, Leone BE, Bonin S, Donada M, Stanta G, Helin K, Lavitrano M. Grassilli E, et al. Among authors: leone be. Clin Cancer Res. 2013 Jul 15;19(14):3820-31. doi: 10.1158/1078-0432.CCR-12-3289. Epub 2013 May 31. Clin Cancer Res. 2013. PMID: 23729362
A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation.
Grassilli E, Pisano F, Cialdella A, Bonomo S, Missaglia C, Cerrito MG, Masiero L, Ianzano L, Giordano F, Cicirelli V, Narloch R, D'Amato F, Noli B, Ferri GL, Leone BE, Stanta G, Bonin S, Helin K, Giovannoni R, Lavitrano M. Grassilli E, et al. Among authors: leone be. Oncogene. 2016 Aug 18;35(33):4368-78. doi: 10.1038/onc.2015.504. Epub 2016 Jan 25. Oncogene. 2016. PMID: 26804170 Free PMC article.
Diet induced mild hypercholesterolemia in pigs: local and systemic inflammation, effects on vascular injury - rescue by high-dose statin treatment.
Busnelli M, Manzini S, Froio A, Vargiolu A, Cerrito MG, Smolenski RT, Giunti M, Cinti A, Zannoni A, Leone BE, Forni M, Bacci ML, Biasi GM, Giovannoni R, Lavitrano M. Busnelli M, et al. Among authors: leone be. PLoS One. 2013 Nov 15;8(11):e80588. doi: 10.1371/journal.pone.0080588. eCollection 2013. PLoS One. 2013. PMID: 24260430 Free PMC article.
APOA-1Milano muteins, orally delivered via genetically modified rice, show anti-atherogenic and anti-inflammatory properties in vitro and in Apoe-/- atherosclerotic mice.
Romano G, Reggi S, Kutryb-Zajac B, Facoetti A, Chisci E, Pettinato M, Giuffrè MR, Vecchio F, Leoni S, De Giorgi M, Avezza F, Cadamuro M, Crippa L, Leone BE, Lavitrano M, Rivolta I, Barisani D, Smolenski RT, Giovannoni R. Romano G, et al. Among authors: leone be. Int J Cardiol. 2018 Nov 15;271:233-239. doi: 10.1016/j.ijcard.2018.04.029. Epub 2018 Jun 13. Int J Cardiol. 2018. PMID: 29907443 Free article.
97 results