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Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo.
Nigro C, Raciti GA, Leone A, Fleming TH, Longo M, Prevenzano I, Fiory F, Mirra P, D'Esposito V, Ulianich L, Nawroth PP, Formisano P, Beguinot F, Miele C. Nigro C, et al. Among authors: leone a. Diabetologia. 2014 Jul;57(7):1485-94. doi: 10.1007/s00125-014-3243-7. Epub 2014 Apr 24. Diabetologia. 2014. PMID: 24759959
The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells.
Mirra P, Nigro C, Prevenzano I, Procopio T, Leone A, Raciti GA, Andreozzi F, Longo M, Fiory F, Beguinot F, Miele C. Mirra P, et al. Among authors: leone a. Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):440-449. doi: 10.1016/j.bbadis.2016.11.018. Epub 2016 Nov 15. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 27864140 Free article.
Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage.
Nigro C, Leone A, Raciti GA, Longo M, Mirra P, Formisano P, Beguinot F, Miele C. Nigro C, et al. Among authors: leone a. Int J Mol Sci. 2017 Jan 18;18(1):188. doi: 10.3390/ijms18010188. Int J Mol Sci. 2017. PMID: 28106778 Free PMC article. Review.
The Destiny of Glucose from a MicroRNA Perspective.
Mirra P, Nigro C, Prevenzano I, Leone A, Raciti GA, Formisano P, Beguinot F, Miele C. Mirra P, et al. Among authors: leone a. Front Endocrinol (Lausanne). 2018 Feb 26;9:46. doi: 10.3389/fendo.2018.00046. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 29535681 Free PMC article. Review.
Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells.
Nigro C, Leone A, Longo M, Prevenzano I, Fleming TH, Nicolò A, Parrillo L, Spinelli R, Formisano P, Nawroth PP, Beguinot F, Miele C. Nigro C, et al. Among authors: leone a. Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):73-85. doi: 10.1016/j.bbadis.2018.10.014. Epub 2018 Oct 18. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30342159 Free article.
1,532 results