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Immunogenicity and safety assessment of a SARS-CoV-2 recombinant spike RBD protein vaccine (Abdala) in paediatric ages 3-18 years old: a double-blinded, multicentre, randomised, phase 1/2 clinical trial (ISMAELILLO study).
Cinza-Estévez Z, Resik-Aguirre S, Figueroa-Baile NL, Oquendo-Martínez R, Campa-Legrá I, Tejeda-Fuentes A, Rivero-Caballero M, González-García G, Chávez-Chong CO, Alonso-Valdés M, Hernández-Bernal F, Lemos-Pérez G, Campal-Espinosa A, Freyre-Corrales G, Benítez-Gordillo D, Gato-Orozco E, Pérez Bartutis GS, Mesa-Pedroso I, Bueno-Alemani N, Infante-Aguilar E, Rodríguez Reinoso JL, Melo-Suarez G, Limonta-Fernández M, Ayala-Ávila M, Muzio-González VL; ISMAELILLO Clinical Trial Group. Cinza-Estévez Z, et al. Among authors: lemos perez g. EClinicalMedicine. 2023 Aug 18;63:102160. doi: 10.1016/j.eclinm.2023.102160. eCollection 2023 Sep. EClinicalMedicine. 2023. PMID: 37649806 Free PMC article.
Evidence of SARS-CoV-2 infection in postmortem lung, kidney, and liver samples, revealing cellular targets involved in COVID-19 pathogenesis.
Falcón-Cama V, Montero-González T, Acosta-Medina EF, Guillen-Nieto G, Berlanga-Acosta J, Fernández-Ortega C, Alfonso-Falcón A, Gilva-Rodríguez N, López-Nocedo L, Cremata-García D, Matos-Terrero M, Pentón-Rol G, Valdés I, Oramas-Díaz L, Suarez-Batista A, Noa-Romero E, Cruz-Sui O, Sánchez D, Borrego-Díaz AI, Valdés-Carreras JE, Vizcaino A, Suárez-Alba J, Valdés-Véliz R, Bergado G, González MA, Hernandez T, Alvarez-Arzola R, Ramírez-Suárez AC, Casillas-Casanova D, Lemos-Pérez G, Blanco-Águila OR, Díaz A, González Y, Bequet-Romero M, Marín-Prida J, Hernández-Perera JC, Del Rosario-Cruz L, Marin-Díaz AP, González-Bravo M, Borrajero I, Acosta-Rivero N. Falcón-Cama V, et al. Among authors: lemos perez g. Arch Virol. 2023 Feb 26;168(3):96. doi: 10.1007/s00705-023-05711-y. Arch Virol. 2023. PMID: 36842152 Free PMC article.
An engineered SARS-CoV-2 receptor-binding domain produced in Pichia pastoris as a candidate vaccine antigen.
Limonta-Fernández M, Chinea-Santiago G, Martín-Dunn AM, Gonzalez-Roche D, Bequet-Romero M, Marquez-Perera G, González-Moya I, Canaan-Haden-Ayala C, Cabrales-Rico A, Espinosa-Rodríguez LA, Ramos-Gómez Y, Andujar-Martínez I, González-López LJ, de la Iglesia MP, Zamora-Sanchez J, Cruz-Sui O, Lemos-Pérez G, Cabrera-Herrera G, Valdes-Hernández J, Martinez-Diaz E, Pimentel-Vazquez E, Ayala-Avila M, Guillén-Nieto G. Limonta-Fernández M, et al. Among authors: lemos perez g. N Biotechnol. 2022 Dec 25;72:11-21. doi: 10.1016/j.nbt.2022.08.002. Epub 2022 Aug 8. N Biotechnol. 2022. PMID: 35953030 Free PMC article.
Safety, tolerability, and immunogenicity of a SARS-CoV-2 recombinant spike RBD protein vaccine: A randomised, double-blind, placebo-controlled, phase 1-2 clinical trial (ABDALA Study).
Hernández-Bernal F, Ricardo-Cobas MC, Martín-Bauta Y, Navarro-Rodríguez Z, Piñera-Martínez M, Quintana-Guerra J, Urrutia-Pérez K, Urrutia-Pérez K, Chávez-Chong CO, Azor-Hernández JL, Rodríguez-Reinoso JL, Lobaina-Lambert L, Colina-Ávila E, Bizet-Almeida J, Rodríguez-Nuviola J, Del Valle-Piñera S, Ramírez-Domínguez M, Tablada-Ferreiro E, Alonso-Valdés M, Lemos-Pérez G, Guillén-Nieto GE, Palenzuela-Díaz A, Noa-Romero E, Limonta-Fernández M, Fernández-Ávila JM, Ali-Mros NA, Del Toro-Lahera L, Remedios-Reyes R, Ayala-Ávila M, Muzio-González VL. Hernández-Bernal F, et al. Among authors: lemos perez g. EClinicalMedicine. 2022 Apr;46:101383. doi: 10.1016/j.eclinm.2022.101383. Epub 2022 Apr 9. EClinicalMedicine. 2022. PMID: 35434578 Free PMC article.