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Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair.
Parisis N, Dans PD, Jbara M, Singh B, Schausi-Tiffoche D, Molina-Serrano D, Brun-Heath I, Hendrychová D, Maity SK, Buitrago D, Lema R, Nait Achour T, Giunta S, Girardot M, Talarek N, Rofidal V, Danezi K, Coudreuse D, Prioleau MN, Feil R, Orozco M, Brik A, Wu PJ, Krasinska L, Fisher D. Parisis N, et al. Among authors: lema r. Nat Commun. 2023 Aug 22;14(1):5104. doi: 10.1038/s41467-023-40843-4. Nat Commun. 2023. PMID: 37607906 Free PMC article.
Impact of DNA methylation on 3D genome structure.
Buitrago D, Labrador M, Arcon JP, Lema R, Flores O, Esteve-Codina A, Blanc J, Villegas N, Bellido D, Gut M, Dans PD, Heath SC, Gut IG, Brun Heath I, Orozco M. Buitrago D, et al. Among authors: lema r. Nat Commun. 2021 May 28;12(1):3243. doi: 10.1038/s41467-021-23142-8. Nat Commun. 2021. PMID: 34050148 Free PMC article.
MiOS, an integrated imaging and computational strategy to model gene folding with nucleosome resolution.
Neguembor MV, Arcon JP, Buitrago D, Lema R, Walther J, Garate X, Martin L, Romero P, AlHaj Abed J, Gut M, Blanc J, Lakadamyali M, Wu CT, Brun Heath I, Orozco M, Dans PD, Cosma MP. Neguembor MV, et al. Among authors: lema r. Nat Struct Mol Biol. 2022 Oct;29(10):1011-1023. doi: 10.1038/s41594-022-00839-y. Epub 2022 Oct 11. Nat Struct Mol Biol. 2022. PMID: 36220894 Free PMC article.
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope.
Orellana L, Thorne AH, Lema R, Gustavsson J, Parisian AD, Hospital A, Cordeiro TN, Bernadó P, Scott AM, Brun-Heath I, Lindahl E, Cavenee WK, Furnari FB, Orozco M. Orellana L, et al. Among authors: lema r. Proc Natl Acad Sci U S A. 2019 May 14;116(20):10009-10018. doi: 10.1073/pnas.1821442116. Epub 2019 Apr 26. Proc Natl Acad Sci U S A. 2019. PMID: 31028138 Free PMC article.
HIV Rapid Testing Programs in Non-Clinical Settings have the Potential to Constitute a Major Diagnostic Option for MSM in Spain.
Balbuena SF, Hoyos J, Belza MJ, Pujol F, Álvarez J, Zulaica D, Zamora C, Rifá B, García-de-Olalla P, Esteso R, Bastida B, Marcos MD, Viver J, Talavera J, Capote L, Lema R, Pastor M, de la Fuente L; Rapid testing in non-clinical settings evaluation group. Balbuena SF, et al. Among authors: lema r. AIDS Behav. 2017 Feb;21(2):525-533. doi: 10.1007/s10461-016-1597-1. AIDS Behav. 2017. PMID: 27807791
Stabilization of apoptotic cells: generation of zombie cells.
Oropesa-Ávila M, Andrade-Talavera Y, Garrido-Maraver J, Cordero MD, de la Mata M, Cotán D, Paz MV, Pavón AD, Alcocer-Gómez E, de Lavera I, Lema R, Zaderenko AP, Rodríguez-Moreno A, Sánchez-Alcázar JA. Oropesa-Ávila M, et al. Among authors: lema r. Cell Death Dis. 2014 Aug 14;5(8):e1369. doi: 10.1038/cddis.2014.332. Cell Death Dis. 2014. PMID: 25118929 Free PMC article.
Apoptotic cells subjected to cold/warming exposure disorganize apoptotic microtubule network and undergo secondary necrosis.
Oropesa-Ávila M, Fernández-Vega A, de la Mata M, Garrido-Maraver J, Cotán D, Paz MV, Pavón AD, Cordero MD, Alcocer-Gómez E, de Lavera I, Lema R, Zaderenko AP, Sánchez-Alcázar JA. Oropesa-Ávila M, et al. Among authors: lema r. Apoptosis. 2014 Sep;19(9):1364-77. doi: 10.1007/s10495-014-1015-y. Apoptosis. 2014. PMID: 25027509
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