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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
1999 1
2001 1
2004 4
2006 1
2012 1
2014 1
2015 2
2017 1
2018 3
2019 1
2020 1
2022 1
2023 6
2024 3

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24 results

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Page 1
A phase I, randomized, ascending-dose study to assess safety, pharmacokinetics, and activity of GDC-8264, a RIP1 inhibitor, in healthy volunteers.
Jones NS, Kshirsagar S, Mohanan V, Ramakrishnan V, Di Nucci F, Ma L, Mao J, Ding H, Klabunde S, Vucic D, Pan L, Lekkerkerker AN, Chen Y, Rothenberg ME. Jones NS, et al. Among authors: lekkerkerker an. Clin Transl Sci. 2023 Oct;16(10):1997-2009. doi: 10.1111/cts.13607. Epub 2023 Aug 24. Clin Transl Sci. 2023. PMID: 37596814 Free PMC article. Clinical Trial.
Astegolimab or Efmarodocokin Alfa in Patients With Severe COVID-19 Pneumonia: A Randomized, Phase 2 Trial.
Waters M, McKinnell JA, Kalil AC, Martin GS, Buchman TG, Theess W, Yang X, Lekkerkerker AN, Staton T, Rosenberger CM, Pappu R, Wang Y, Zhang W, Brooks L, Cheung D, Galanter J, Chen H, Mohan D, Peck MC; COVID-astegolimab-interleukin (IL) (COVASTIL) Study Group. Waters M, et al. Among authors: lekkerkerker an. Crit Care Med. 2023 Jan 1;51(1):103-116. doi: 10.1097/CCM.0000000000005716. Epub 2022 Nov 14. Crit Care Med. 2023. PMID: 36519984 Free PMC article. Clinical Trial.
SAkuraBONSAI: Protocol design of a novel, prospective study to explore clinical, imaging, and biomarker outcomes in patients with AQP4-IgG-seropositive neuromyelitis optica spectrum disorder receiving open-label satralizumab.
Bennett JL, Fujihara K, Kim HJ, Marignier R, O'Connor KC, Sergott RC, Traboulsee A, Wiendl H, Wuerfel J, Zamvil SS, Anania VG, Buffels R, Künzel T, Lekkerkerker AN, Lennon-Chrimes S, Pittock SJ. Bennett JL, et al. Among authors: lekkerkerker an. Front Neurol. 2023 Feb 17;14:1114667. doi: 10.3389/fneur.2023.1114667. eCollection 2023. Front Neurol. 2023. PMID: 36873431 Free PMC article.
Cellular players in lung fibrosis.
Lekkerkerker AN, Aarbiou J, van Es T, Janssen RA. Lekkerkerker AN, et al. Curr Pharm Des. 2012;18(27):4093-102. doi: 10.2174/138161212802430396. Curr Pharm Des. 2012. PMID: 22630084 Review.
SYK is a candidate kinase target for the treatment of advanced prostate cancer.
Ghotra VP, He S, van der Horst G, Nijhoff S, de Bont H, Lekkerkerker A, Janssen R, Jenster G, van Leenders GJ, Hoogland AM, Verhoef EI, Baranski Z, Xiong J, van de Water B, van der Pluijm G, Snaar-Jagalska BE, Danen EH. Ghotra VP, et al. Among authors: lekkerkerker a. Cancer Res. 2015 Jan 1;75(1):230-40. doi: 10.1158/0008-5472.CAN-14-0629. Epub 2014 Nov 11. Cancer Res. 2015. PMID: 25388286
Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases.
Stefanich EG, Rae J, Sukumaran S, Lutman J, Lekkerkerker A, Ouyang W, Wang X, Lee D, Danilenko DM, Diehl L, Loyet KM, Herman A. Stefanich EG, et al. Among authors: lekkerkerker a. Biochem Pharmacol. 2018 Jun;152:224-235. doi: 10.1016/j.bcp.2018.03.031. Epub 2018 Mar 31. Biochem Pharmacol. 2018. PMID: 29608910
Nonclinical safety assessment of a human interleukin-22FC IG fusion protein demonstrates in vitro to in vivo and cross-species translatability.
Lee DW, Zhong S, Pai R, Rae J, Sukumaran S, Stefanich EG, Lutman J, Doudement E, Wang X, Harder B, Lekkerkerker A, Herman A, Ouyang W, Danilenko DM. Lee DW, et al. Among authors: lekkerkerker a. Pharmacol Res Perspect. 2018 Nov 15;6(6):e00434. doi: 10.1002/prp2.434. eCollection 2018 Dec. Pharmacol Res Perspect. 2018. PMID: 30464842 Free PMC article.
24 results