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Page 1
Intrahepatic microbes govern liver immunity by programming NKT cells.
Leinwand JC, Paul B, Chen R, Xu F, Sierra MA, Paluru MM, Nanduri S, Alcantara CG, Shadaloey SA, Yang F, Adam SA, Li Q, Bandel M, Gakhal I, Appiah L, Guo Y, Vardhan M, Flaminio Z, Grodman ER, Mermelstein A, Wang W, Diskin B, Aykut B, Khan M, Werba G, Pushalkar S, McKinstry M, Kluger Z, Park JJ, Hsieh B, Dancel-Manning K, Liang FX, Park JS, Saxena A, Li X, Theise ND, Saxena D, Miller G. Leinwand JC, et al. J Clin Invest. 2022 Apr 15;132(8):e151725. doi: 10.1172/JCI151725. J Clin Invest. 2022. PMID: 35175938 Free PMC article.
Innate αβ T Cells Mediate Antitumor Immunity by Orchestrating Immunogenic Macrophage Programming.
Hundeyin M, Kurz E, Mishra A, Rossi JAK, Liudahl SM, Leis KR, Mehrotra H, Kim M, Torres LE, Ogunsakin A, Link J, Sears RC, Sivagnanam S, Goecks J, Islam KMS, Dolgalev I, Savadkar S, Wang W, Aykut B, Leinwand J, Diskin B, Adam S, Israr M, Gelas M, Lish J, Chin K, Farooq MS, Wadowski B, Wu J, Shah S, Adeegbe DO, Pushalkar S, Vasudevaraja V, Saxena D, Wong KK, Coussens LM, Miller G. Hundeyin M, et al. Cancer Discov. 2019 Sep;9(9):1288-1305. doi: 10.1158/2159-8290.CD-19-0161. Epub 2019 Jul 2. Cancer Discov. 2019. PMID: 31266770 Free PMC article.
γδ T Cells Promote Steatohepatitis by Orchestrating Innate and Adaptive Immune Programming.
Torres-Hernandez A, Wang W, Nikiforov Y, Tejada K, Torres L, Kalabin A, Adam S, Wu J, Lu L, Chen R, Lemmer A, Camargo J, Hundeyin M, Diskin B, Aykut B, Kurz E, Kochen Rossi JA, Khan M, Liria M, Sanchez G, Wu N, Su W, Adams S, Haq MIU, Farooq MS, Vasudevaraja V, Leinwand J, Miller G. Torres-Hernandez A, et al. Hepatology. 2020 Feb;71(2):477-494. doi: 10.1002/hep.30952. Epub 2019 Dec 31. Hepatology. 2020. PMID: 31529720
The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL.
Aykut B, Pushalkar S, Chen R, Li Q, Abengozar R, Kim JI, Shadaloey SA, Wu D, Preiss P, Verma N, Guo Y, Saxena A, Vardhan M, Diskin B, Wang W, Leinwand J, Kurz E, Kochen Rossi JA, Hundeyin M, Zambrinis C, Li X, Saxena D, Miller G. Aykut B, et al. Nature. 2019 Oct;574(7777):264-267. doi: 10.1038/s41586-019-1608-2. Epub 2019 Oct 2. Nature. 2019. PMID: 31578522 Free PMC article.
Targeting Piezo1 unleashes innate immunity against cancer and infectious disease.
Aykut B, Chen R, Kim JI, Wu D, Shadaloey SAA, Abengozar R, Preiss P, Saxena A, Pushalkar S, Leinwand J, Diskin B, Wang W, Werba G, Berman M, Lee SKB, Khodadadi-Jamayran A, Saxena D, Coetzee WA, Miller G. Aykut B, et al. Sci Immunol. 2020 Aug 21;5(50):eabb5168. doi: 10.1126/sciimmunol.abb5168. Sci Immunol. 2020. PMID: 32826342
Targeting SYK signaling in myeloid cells protects against liver fibrosis and hepatocarcinogenesis.
Torres-Hernandez A, Wang W, Nikiforov Y, Tejada K, Torres L, Kalabin A, Wu Y, Haq MIU, Khan MY, Zhao Z, Su W, Camargo J, Hundeyin M, Diskin B, Adam S, Rossi JAK, Kurz E, Aykut B, Shadaloey SAA, Leinwand J, Miller G. Torres-Hernandez A, et al. Oncogene. 2019 Jun;38(23):4512-4526. doi: 10.1038/s41388-019-0734-5. Epub 2019 Feb 11. Oncogene. 2019. PMID: 30742098
BTLA+CD200+ B cells dictate the divergent immune landscape and immunotherapeutic resistance in metastatic vs. primary pancreatic cancer.
Diskin B, Adam S, Soto GS, Liria M, Aykut B, Sundberg B, Li E, Leinwand J, Chen R, Kim M, Salas RD, Cassini MF, Buttar C, Wang W, Farooq MS, Shadaloey SAA, Werba G, Fnu A, Yang F, Hirsch C, Glinski J, Panjwani A, Weitzner Y, Cohen D, Asghar U, Miller G. Diskin B, et al. Oncogene. 2022 Sep;41(38):4349-4360. doi: 10.1038/s41388-022-02425-4. Epub 2022 Aug 10. Oncogene. 2022. PMID: 35948648
The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression.
Pushalkar S, Hundeyin M, Daley D, Zambirinis CP, Kurz E, Mishra A, Mohan N, Aykut B, Usyk M, Torres LE, Werba G, Zhang K, Guo Y, Li Q, Akkad N, Lall S, Wadowski B, Gutierrez J, Kochen Rossi JA, Herzog JW, Diskin B, Torres-Hernandez A, Leinwand J, Wang W, Taunk PS, Savadkar S, Janal M, Saxena A, Li X, Cohen D, Sartor RB, Saxena D, Miller G. Pushalkar S, et al. Cancer Discov. 2018 Apr;8(4):403-416. doi: 10.1158/2159-8290.CD-17-1134. Epub 2018 Mar 22. Cancer Discov. 2018. PMID: 29567829 Free PMC article.
26 results