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STING controls nociception via type I interferon signalling in sensory neurons.
Donnelly CR, Jiang C, Andriessen AS, Wang K, Wang Z, Ding H, Zhao J, Luo X, Lee MS, Lei YL, Maixner W, Ko MC, Ji RR. Donnelly CR, et al. Among authors: lei yl. Nature. 2021 Mar;591(7849):275-280. doi: 10.1038/s41586-020-03151-1. Epub 2021 Jan 13. Nature. 2021. PMID: 33442058 Free PMC article.
Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING.
Heath BR, Gong W, Taner HF, Broses L, Okuyama K, Cheng W, Jin M, Fitzsimonds ZR, Manousidaki A, Wu Y, Zhang S, Wen H, Chinn SB, Bartee E, Xie Y, Moon JJ, Lei YL. Heath BR, et al. Among authors: lei yl. Cell Rep. 2023 Apr 25;42(4):112303. doi: 10.1016/j.celrep.2023.112303. Epub 2023 Mar 22. Cell Rep. 2023. PMID: 36952341 Free PMC article.
Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine.
Tan YS, Sansanaphongpricha K, Xie Y, Donnelly CR, Luo X, Heath BR, Zhao X, Bellile E, Hu H, Chen H, Polverini PJ, Chen Q, Young S, Carey TE, Nör JE, Ferris RL, Wolf GT, Sun D, Lei YL. Tan YS, et al. Among authors: lei yl. Clin Cancer Res. 2018 Sep 1;24(17):4242-4255. doi: 10.1158/1078-0432.CCR-17-2807. Epub 2018 May 16. Clin Cancer Res. 2018. PMID: 29769207 Free PMC article.
Head and Neck Cancer Immunotherapy beyond the Checkpoint Blockade.
Heath BR, Michmerhuizen NL, Donnelly CR, Sansanaphongpricha K, Sun D, Brenner JC, Lei YL. Heath BR, et al. Among authors: lei yl. J Dent Res. 2019 Sep;98(10):1073-1080. doi: 10.1177/0022034519864112. Epub 2019 Jul 24. J Dent Res. 2019. PMID: 31340724 Free PMC article. Review.
HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING.
Luo X, Donnelly CR, Gong W, Heath BR, Hao Y, Donnelly LA, Moghbeli T, Tan YS, Lin X, Bellile E, Kansy BA, Carey TE, Brenner JC, Cheng L, Polverini PJ, Morgan MA, Wen H, Prince ME, Ferris RL, Xie Y, Young S, Wolf GT, Chen Q, Lei YL. Luo X, et al. Among authors: lei yl. J Clin Invest. 2020 Apr 1;130(4):1635-1652. doi: 10.1172/JCI129497. J Clin Invest. 2020. PMID: 31874109 Free PMC article.
121 results