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Physiologically based pharmacokinetic modeling of tacrolimus for food-drug and CYP3A drug-drug-gene interaction predictions.
Loer HLH, Feick D, Rüdesheim S, Selzer D, Schwab M, Teutonico D, Frechen S, van der Lee M, Moes DJAR, Swen JJ, Lehr T. Loer HLH, et al. Among authors: lehr t. CPT Pharmacometrics Syst Pharmacol. 2023 May;12(5):724-738. doi: 10.1002/psp4.12946. Epub 2023 Mar 10. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36808892 Free PMC article.
Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study.
Tura A, Grespan E, Göbl CS, Koivula RW, Franks PW, Pearson ER, Walker M, Forgie IM, Giordano GN, Pavo I, Ruetten H, Dermitzakis ET, McCarthy MI, Pedersen O, Schwenk JM, Adamski J, De Masi F, Tsirigos KD, Brunak S, Viñuela A, Mahajan A, McDonald TJ, Kokkola T, Vangipurapu J, Cederberg H, Laakso M, Rutters F, Elders PJM, Koopman ADM, Beulens JW, Ridderstråle M, Hansen TH, Allin KH, Hansen T, Vestergaard H, Mari A; IMI DIRECT Consortium. Tura A, et al. Diabetes. 2021 Sep;70(9):2092-2106. doi: 10.2337/db21-0227. Epub 2021 Jul 7. Diabetes. 2021. PMID: 34233929
MDM2 antagonist nutlin-3a sensitizes tumors to V-ATPase inhibition.
Schneider LS, Ulrich M, Lehr T, Menche D, Müller R, von Schwarzenberg K. Schneider LS, et al. Among authors: lehr t. Mol Oncol. 2016 Aug;10(7):1054-62. doi: 10.1016/j.molonc.2016.04.005. Epub 2016 Apr 27. Mol Oncol. 2016. PMID: 27157929 Free PMC article.
Effective elimination of dabigatran by haemodialysis. A phase I single-centre study in patients with end-stage renal disease.
Khadzhynov D, Wagner F, Formella S, Wiegert E, Moschetti V, Slowinski T, Neumayer HH, Liesenfeld KH, Lehr T, Härtter S, Friedman J, Peters H, Clemens A. Khadzhynov D, et al. Among authors: lehr t. Thromb Haemost. 2013 Apr;109(4):596-605. doi: 10.1160/TH12-08-0573. Epub 2013 Feb 7. Thromb Haemost. 2013. PMID: 23389759 Clinical Trial.
A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: THE Randomized, phase II study to evaluate the safety and pharmacokinetics of oral dabigatran etexilate in patients after heart valve replacement (RE-ALIGN).
Van de Werf F, Brueckmann M, Connolly SJ, Friedman J, Granger CB, Härtter S, Harper R, Kappetein AP, Lehr T, Mack MJ, Noack H, Eikelboom JW. Van de Werf F, et al. Among authors: lehr t. Am Heart J. 2012 Jun;163(6):931-937.e1. doi: 10.1016/j.ahj.2012.03.011. Am Heart J. 2012. PMID: 22709744 Clinical Trial.
Genetic determinants of dabigatran plasma levels and their relation to bleeding.
Paré G, Eriksson N, Lehr T, Connolly S, Eikelboom J, Ezekowitz MD, Axelsson T, Haertter S, Oldgren J, Reilly P, Siegbahn A, Syvanen AC, Wadelius C, Wadelius M, Zimdahl-Gelling H, Yusuf S, Wallentin L. Paré G, et al. Among authors: lehr t. Circulation. 2013 Apr 2;127(13):1404-12. doi: 10.1161/CIRCULATIONAHA.112.001233. Epub 2013 Mar 6. Circulation. 2013. PMID: 23467860 Clinical Trial.
133 results