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Novel models for the prediction of drug-gene interactions.
Türk D, Fuhr LM, Marok FZ, Rüdesheim S, Kühn A, Selzer D, Schwab M, Lehr T. Türk D, et al. Among authors: lehr t. Expert Opin Drug Metab Toxicol. 2021 Nov;17(11):1293-1310. doi: 10.1080/17425255.2021.1998455. Epub 2021 Nov 15. Expert Opin Drug Metab Toxicol. 2021. PMID: 34727800
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.
Wilman HR, Parisinos CA, Atabaki-Pasdar N, Kelly M, Thomas EL, Neubauer S; IMI DIRECT Consortium; Mahajan A, Hingorani AD, Patel RS, Hemingway H, Franks PW, Bell JD, Banerjee R, Yaghootkar H. Wilman HR, et al. J Hepatol. 2019 Sep;71(3):594-602. doi: 10.1016/j.jhep.2019.05.032. Epub 2019 Jun 19. J Hepatol. 2019. PMID: 31226389 Free PMC article.
Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon.
Ramharter M, Schwab M, Mombo-Ngoma G, Zoleko Manego R, Akerey-Diop D, Basra A, Mackanga JR, Würbel H, Wojtyniak JG, Gonzalez R, Hofmann U, Geditz M, Matsiegui PB, Kremsner PG, Menendez C, Kerb R, Lehr T. Ramharter M, et al. Among authors: lehr t. Antimicrob Agents Chemother. 2019 Jan 29;63(2):e01113-18. doi: 10.1128/AAC.01113-18. Print 2019 Feb. Antimicrob Agents Chemother. 2019. PMID: 30455233 Free PMC article.
Physiologically-Based Pharmacokinetic Models for CYP1A2 Drug-Drug Interaction Prediction: A Modeling Network of Fluvoxamine, Theophylline, Caffeine, Rifampicin, and Midazolam.
Britz H, Hanke N, Volz AK, Spigset O, Schwab M, Eissing T, Wendl T, Frechen S, Lehr T. Britz H, et al. Among authors: lehr t. CPT Pharmacometrics Syst Pharmacol. 2019 May;8(5):296-307. doi: 10.1002/psp4.12397. Epub 2019 Mar 13. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 30762305 Free PMC article.
Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole.
Türk D, Hanke N, Wolf S, Frechen S, Eissing T, Wendl T, Schwab M, Lehr T. Türk D, et al. Among authors: lehr t. Clin Pharmacokinet. 2019 Dec;58(12):1595-1607. doi: 10.1007/s40262-019-00777-x. Clin Pharmacokinet. 2019. PMID: 31129789 Free PMC article.
133 results