Lehr P - Search Results

1

Structure of lipoprotein lipase in complex with GPIHBP1.

Arora R, Nimonkar AV, Baird D, Wang C, Chiu CH, Horton PA, Hanrahan S, Cubbon R, Weldon S, Tschantz WR, Mueller S, Brunner R, Lehr P, Meier P, Ottl J, Voznesensky A, Pandey P, Smith TM, Stojanovic A, Flyer A, Benson TE, Romanowski MJ, Trauger JW. Arora R, et al. Among authors: lehr p. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10360-10365. doi: 10.1073/pnas.1820171116. Epub 2019 May 9. Proc Natl Acad Sci U S A. 2019. PMID: 31072929 Free PMC article.

2

N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase.

Lehr P, Billich A, Wolff B, Nussbaumer P. Lehr P, et al. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1235-8. doi: 10.1016/j.bmcl.2004.11.069. Bioorg Med Chem Lett. 2005. PMID: 15686949

3

2-Substituted 4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.

Nussbaumer P, Lehr P, Billich A. Nussbaumer P, et al. Among authors: lehr p. J Med Chem. 2002 Sep 12;45(19):4310-20. doi: 10.1021/jm020878w. J Med Chem. 2002. PMID: 12213072

4

Nortropinyl-arylsulfonylureas as novel, reversible inhibitors of human steroid sulfatase.

Nussbaumer P, Geyl D, Horvath A, Lehr P, Wolff B, Billich A. Nussbaumer P, et al. Among authors: lehr p. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3673-7. doi: 10.1016/j.bmcl.2003.08.019. Bioorg Med Chem Lett. 2003. PMID: 14552755

5

Inhibitors of human immunodeficiency virus type 1 protease containing 2-aminobenzyl-substituted 4-amino-3-hydroxy-5-phenylpentanoic acid: synthesis, activity, and oral bioavailability.

Lehr P, Billich A, Charpiot B, Ettmayer P, Scholz D, Rosenwirth B, Gstach H. Lehr P, et al. J Med Chem. 1996 May 10;39(10):2060-7. doi: 10.1021/jm9508696. J Med Chem. 1996. PMID: 8642565

6

Stimulation of MCF-7 breast cancer cell proliferation by estrone sulfate and dehydroepiandrosterone sulfate: inhibition by novel non-steroidal steroid sulfatase inhibitors.

Billich A, Nussbaumer P, Lehr P. Billich A, et al. Among authors: lehr p. J Steroid Biochem Mol Biol. 2000 Jul-Aug;73(5):225-35. doi: 10.1016/s0960-0760(00)00077-7. J Steroid Biochem Mol Biol. 2000. PMID: 11070351

7

Inhibitors of HIV-1 proteinase containing 2-heterosubstituted 4-amino-3-hydroxy-5-phenylpentanoic acid: synthesis, enzyme inhibition, and antiviral activity.

Scholz D, Billich A, Charpiot B, Ettmayer P, Lehr P, Rosenwirth B, Schreiner E, Gstach H. Scholz D, et al. Among authors: lehr p. J Med Chem. 1994 Sep 16;37(19):3079-89. doi: 10.1021/jm00045a013. J Med Chem. 1994. PMID: 7932531

8

SDZ PRI 053, an orally bioavailable human immunodeficiency virus type 1 proteinase inhibitor containing the 2-aminobenzylstatine moiety.

Billich A, Fricker G, Müller I, Donatsch P, Ettmayer P, Gstach H, Lehr P, Peichl P, Scholz D, Rosenwirth B. Billich A, et al. Among authors: lehr p. Antimicrob Agents Chemother. 1995 Jul;39(7):1406-13. doi: 10.1128/AAC.39.7.1406. Antimicrob Agents Chemother. 1995. PMID: 7492076 Free PMC article.

9

HIV proteinase inhibitors containing 2-aminobenzylstatine as a novel scissile bond replacement: biochemical and pharmacological characterization.

Billich A, Charpiot B, Fricker G, Gstach H, Lehr P, Peichl P, Scholz D, Rosenwirth B. Billich A, et al. Among authors: lehr p. Antiviral Res. 1994 Dec;25(3-4):215-33. doi: 10.1016/0166-3542(94)90005-1. Antiviral Res. 1994. PMID: 7710270

10

Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1β.

Hommel U, Hurth K, Rondeau JM, Vulpetti A, Ostermeier D, Boettcher A, Brady JP, Hediger M, Lehmann S, Koch E, Blechschmidt A, Yamamoto R, Tundo Dottorello V, Haenni-Holzinger S, Kaiser C, Lehr P, Lingel A, Mureddu L, Schleberger C, Blank J, Ramage P, Freuler F, Eder J, Bornancin F. Hommel U, et al. Among authors: lehr p. Nat Commun. 2023 Sep 7;14(1):5497. doi: 10.1038/s41467-023-41190-0. Nat Commun. 2023. PMID: 37679328 Free PMC article.

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