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Development of 5-fluorouracil-dichloroacetate mutual prodrugs as anticancer agents.
Mironiuk-Puchalska E, Karatsai O, Żuchowska A, Wróblewski W, Borys F, Lehka L, Rędowicz MJ, Koszytkowska-Stawińska M. Mironiuk-Puchalska E, et al. Among authors: lehka l. Bioorg Chem. 2023 Nov;140:106784. doi: 10.1016/j.bioorg.2023.106784. Epub 2023 Aug 23. Bioorg Chem. 2023. PMID: 37639758 Free article.
Cannabimimetic N-Stearoylethanolamine as "Double-Edged Sword" in Anticancer Chemotherapy: Proapoptotic Effect on Tumor Cells and Suppression of Tumor Growth versus Its Bio-Protective Actions in Complex with Polymeric Carrier on General Toxicity of Doxorubicin In Vivo.
Panchuk R, Skorokhyd N, Chumak V, Lehka L, Kosiakova H, Horid'ko T, Hudz I, Hula N, Riabtseva A, Mitina N, Zaichenko A, Heffeter P, Berger W, Stoika R. Panchuk R, et al. Among authors: lehka l. Pharmaceutics. 2023 Mar 3;15(3):835. doi: 10.3390/pharmaceutics15030835. Pharmaceutics. 2023. PMID: 36986696 Free PMC article.
P2X7 receptor: the regulator of glioma tumor development and survival.
Matyśniak D, Chumak V, Nowak N, Kukla A, Lehka L, Oslislok M, Pomorski P. Matyśniak D, et al. Among authors: lehka l. Purinergic Signal. 2022 Mar;18(1):135-154. doi: 10.1007/s11302-021-09834-2. Epub 2021 Dec 29. Purinergic Signal. 2022. PMID: 34964926 Free PMC article.
Rapid generation of hydrogen peroxide contributes to the complex cell death induction by the angucycline antibiotic landomycin E.
Panchuk RR, Lehka LV, Terenzi A, Matselyukh BP, Rohr J, Jha AK, Downey T, Kril IJ, Herbacek I, van Schoonhoven S, Heffeter P, Stoika RS, Berger W. Panchuk RR, et al. Among authors: lehka lv. Free Radic Biol Med. 2017 May;106:134-147. doi: 10.1016/j.freeradbiomed.2017.02.024. Epub 2017 Feb 9. Free Radic Biol Med. 2017. PMID: 28189848 Free PMC article.
14 results