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Effects of exogenous ghrelin administration and ghrelin receptor blockade, in combination with alcohol, on peripheral inflammatory markers in heavy-drinking individuals: Results from two human laboratory studies.
Farokhnia M, Portelli J, Lee MR, McDiarmid GR, Munjal V, Abshire KM, Battista JT, Browning BD, Deschaine SL, Akhlaghi F, Leggio L. Farokhnia M, et al. Among authors: leggio l. Brain Res. 2020 Aug 1;1740:146851. doi: 10.1016/j.brainres.2020.146851. Epub 2020 Apr 24. Brain Res. 2020. PMID: 32339499 Free PMC article. Clinical Trial.
Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies.
Farokhnia M, Rentsch CT, Chuong V, McGinn MA, Elvig SK, Douglass EA, Gonzalez LA, Sanfilippo JE, Marchette RCN, Tunstall BJ, Fiellin DA, Koob GF, Justice AC, Leggio L, Vendruscolo LF. Farokhnia M, et al. Among authors: leggio l. Mol Psychiatry. 2022 Nov;27(11):4642-4652. doi: 10.1038/s41380-022-01736-y. Epub 2022 Sep 20. Mol Psychiatry. 2022. PMID: 36123420 Free PMC article.
The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence.
Suchankova P, Yan J, Schwandt ML, Stangl BL, Caparelli EC, Momenan R, Jerlhag E, Engel JA, Hodgkinson CA, Egli M, Lopez MF, Becker HC, Goldman D, Heilig M, Ramchandani VA, Leggio L. Suchankova P, et al. Among authors: leggio l. Transl Psychiatry. 2015 Jun 16;5(6):e583. doi: 10.1038/tp.2015.68. Transl Psychiatry. 2015. PMID: 26080318 Free PMC article.
Defining the role of corticotropin releasing factor binding protein in alcohol consumption.
Haass-Koffler CL, Henry AT, Melkus G, Simms JA, Naemmuddin M, Nielsen CK, Lasek AW, Magill M, Schwandt ML, Momenan R, Hodgkinson CA, Bartlett SE, Swift RM, Bonci A, Leggio L. Haass-Koffler CL, et al. Among authors: leggio l. Transl Psychiatry. 2016 Nov 15;6(11):e953. doi: 10.1038/tp.2016.208. Transl Psychiatry. 2016. PMID: 27845775 Free PMC article.
447 results