Legewie S - Search Results

1

Data-based stochastic modeling reveals sources of activity bursts in single-cell TGF-β signaling.

Kolbe N, Hexemer L, Bammert LM, Loewer A, Lukáčová-Medvid'ová M, Legewie S. Kolbe N, et al. Among authors: legewie s. PLoS Comput Biol. 2022 Jun 27;18(6):e1010266. doi: 10.1371/journal.pcbi.1010266. eCollection 2022 Jun. PLoS Comput Biol. 2022. PMID: 35759468 Free PMC article.

2

Determinants of cell-to-cell variability in protein kinase signaling.

Jeschke M, Baumgärtner S, Legewie S. Jeschke M, et al. Among authors: legewie s. PLoS Comput Biol. 2013;9(12):e1003357. doi: 10.1371/journal.pcbi.1003357. Epub 2013 Dec 5. PLoS Comput Biol. 2013. PMID: 24339758 Free PMC article.

3

Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels.

Strasen J, Sarma U, Jentsch M, Bohn S, Sheng C, Horbelt D, Knaus P, Legewie S, Loewer A. Strasen J, et al. Among authors: legewie s. Mol Syst Biol. 2018 Jan 25;14(1):e7733. doi: 10.15252/msb.20177733. Mol Syst Biol. 2018. PMID: 29371237 Free PMC article.

4

A multi-scale model of hepcidin promoter regulation reveals factors controlling systemic iron homeostasis.

Casanovas G, Banerji A, d'Alessio F, Muckenthaler MU, Legewie S. Casanovas G, et al. Among authors: legewie s. PLoS Comput Biol. 2014 Jan;10(1):e1003421. doi: 10.1371/journal.pcbi.1003421. Epub 2014 Jan 2. PLoS Comput Biol. 2014. PMID: 24391488 Free PMC article.

5

Correlated receptor transport processes buffer single-cell heterogeneity.

Kallenberger SM, Unger AL, Legewie S, Lymperopoulos K, Klingmüller U, Eils R, Herten DP. Kallenberger SM, et al. Among authors: legewie s. PLoS Comput Biol. 2017 Sep 25;13(9):e1005779. doi: 10.1371/journal.pcbi.1005779. eCollection 2017 Sep. PLoS Comput Biol. 2017. PMID: 28945754 Free PMC article.

6

Ultrasensitization: switch-like regulation of cellular signaling by transcriptional induction.

Legewie S, Blüthgen N, Schäfer R, Herzel H. Legewie S, et al. PLoS Comput Biol. 2005 Oct;1(5):e54. doi: 10.1371/journal.pcbi.0010054. Epub 2005 Oct 28. PLoS Comput Biol. 2005. PMID: 16261195 Free PMC article.

7

Estrogen-dependent control and cell-to-cell variability of transcriptional bursting.

Fritzsch C, Baumgärtner S, Kuban M, Steinshorn D, Reid G, Legewie S. Fritzsch C, et al. Among authors: legewie s. Mol Syst Biol. 2018 Feb 23;14(2):e7678. doi: 10.15252/msb.20177678. Mol Syst Biol. 2018. PMID: 29476006 Free PMC article.

8

Position-dependent effects of RNA-binding proteins in the context of co-transcriptional splicing.

Horn T, Gosliga A, Li C, Enculescu M, Legewie S. Horn T, et al. Among authors: legewie s. NPJ Syst Biol Appl. 2023 Jan 18;9(1):1. doi: 10.1038/s41540-022-00264-3. NPJ Syst Biol Appl. 2023. PMID: 36653378 Free PMC article.

9

Modelling Systemic Iron Regulation during Dietary Iron Overload and Acute Inflammation: Role of Hepcidin-Independent Mechanisms.

Enculescu M, Metzendorf C, Sparla R, Hahnel M, Bode J, Muckenthaler MU, Legewie S. Enculescu M, et al. Among authors: legewie s. PLoS Comput Biol. 2017 Jan 9;13(1):e1005322. doi: 10.1371/journal.pcbi.1005322. eCollection 2017 Jan. PLoS Comput Biol. 2017. PMID: 28068331 Free PMC article.

10

Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability.

Legewie S, Blüthgen N, Herzel H. Legewie S, et al. PLoS Comput Biol. 2006 Sep 15;2(9):e120. doi: 10.1371/journal.pcbi.0020120. Epub 2006 Jul 28. PLoS Comput Biol. 2006. PMID: 16978046 Free PMC article.

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