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Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload.
Bartoli F, Bailey MA, Rode B, Mateo P, Antigny F, Bedouet K, Gerbaud P, Gosain R, Plante J, Norman K, Gomez S, Lefebvre F, Rucker-Martin C, Ainscough JFX, Kearney MT, Bruns AF, Shi J, Appleby HL, Young RS, Shawer HM, Debant M, Gomez AM, Beech DJ, Foster R, Benitah JP, Sabourin J. Bartoli F, et al. Among authors: lefebvre f. Circulation. 2020 Jan 21;141(3):199-216. doi: 10.1161/CIRCULATIONAHA.118.038891. Epub 2020 Jan 7. Circulation. 2020. PMID: 31906693 Free PMC article.
Specific Activation of the Alternative Cardiac Promoter of Cacna1c by the Mineralocorticoid Receptor.
Mesquita TR, Auguste G, Falcón D, Ruiz-Hurtado G, Salazar-Enciso R, Sabourin J, Lefebvre F, Viengchareun S, Kobeissy H, Lechène P, Nicolas V, Fernandez-Celis A, Gómez S, Lauton Santos S, Morel E, Rueda A, López-Andrés N, Gómez AM, Lombès M, Benitah JP. Mesquita TR, et al. Among authors: lefebvre f. Circ Res. 2018 Mar 30;122(7):e49-e61. doi: 10.1161/CIRCRESAHA.117.312451. Epub 2018 Feb 21. Circ Res. 2018. PMID: 29467196
Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure.
Karam S, Margaria JP, Bourcier A, Mika D, Varin A, Bedioune I, Lindner M, Bouadjel K, Dessillons M, Gaudin F, Lefebvre F, Mateo P, Lechène P, Gomez S, Domergue V, Robert P, Coquard C, Algalarrondo V, Samuel JL, Michel JB, Charpentier F, Ghigo A, Hirsch E, Fischmeister R, Leroy J, Vandecasteele G. Karam S, et al. Among authors: lefebvre f. Circulation. 2020 Jul 14;142(2):161-174. doi: 10.1161/CIRCULATIONAHA.119.042573. Epub 2020 Apr 8. Circulation. 2020. PMID: 32264695
Activation of sarcolipin expression and altered calcium cycling in LMNA cardiomyopathy.
Morales Rodriguez B, Domínguez-Rodríguez A, Benitah JP, Lefebvre F, Marais T, Mougenot N, Beauverger P, Bonne G, Briand V, Gómez AM, Muchir A. Morales Rodriguez B, et al. Among authors: lefebvre f. Biochem Biophys Rep. 2020 May 18;22:100767. doi: 10.1016/j.bbrep.2020.100767. eCollection 2020 Jul. Biochem Biophys Rep. 2020. PMID: 32490213 Free PMC article.
Synergic PDE3 and PDE4 control intracellular cAMP and cardiac excitation-contraction coupling in a porcine model.
Mika D, Bobin P, Lindner M, Boet A, Hodzic A, Lefebvre F, Lechène P, Sadoune M, Samuel JL, Algalarrondo V, Rucker-Martin C, Lambert V, Fischmeister R, Vandecasteele G, Leroy J. Mika D, et al. Among authors: lefebvre f. J Mol Cell Cardiol. 2019 Aug;133:57-66. doi: 10.1016/j.yjmcc.2019.05.025. Epub 2019 May 31. J Mol Cell Cardiol. 2019. PMID: 31158360
Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice.
Leroy J, Richter W, Mika D, Castro LR, Abi-Gerges A, Xie M, Scheitrum C, Lefebvre F, Schittl J, Mateo P, Westenbroek R, Catterall WA, Charpentier F, Conti M, Fischmeister R, Vandecasteele G. Leroy J, et al. Among authors: lefebvre f. J Clin Invest. 2011 Jul;121(7):2651-61. doi: 10.1172/JCI44747. Epub 2011 Jun 13. J Clin Invest. 2011. PMID: 21670503 Free PMC article.
Standard and Strain Measurements by Echocardiography Detect Early Overloaded Right Ventricular Dysfunction: Validation against Hemodynamic and Myocyte Contractility Changes in a Large Animal Model.
Hodzic A, Bobin P, Mika D, Ly M, Lefebvre F, Lechêne P, Le Bret E, Gouadon E, Coblence M, Vandecasteele G, Capderou A, Leroy J, Rucker-Martin C, Lambert V. Hodzic A, et al. Among authors: lefebvre f. J Am Soc Echocardiogr. 2017 Nov;30(11):1138-1147.e4. doi: 10.1016/j.echo.2017.07.003. Epub 2017 Aug 30. J Am Soc Echocardiogr. 2017. PMID: 28864150
445 results