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Discovery of Benzopyridone-Based Transient Receptor Potential Vanilloid 1 Agonists and Antagonists and the Structural Elucidation of Their Activity Shift.
Thorat SA, Lee Y, Jung A, Ann J, Ahn S, Baek J, Zuo D, Do N, Jeong JJ, Blumberg PM, Esch TE, Turcios NA, Pearce LV, Ha HJ, Yoo YD, Hong S, Choi S, Lee J. Thorat SA, et al. Among authors: lee y, lee j. J Med Chem. 2021 Jan 14;64(1):370-384. doi: 10.1021/acs.jmedchem.0c00982. Epub 2021 Jan 1. J Med Chem. 2021. PMID: 33385210
Design, synthesis, and molecular modeling studies of 5'-deoxy-5'-ureidoadenosine: 5'-ureido group as multiple hydrogen bonding donor in the active site of S-adenosylhomocysteine hydrolase.
Wang T, Lee HJ, Tosh DK, Kim HO, Pal S, Choi S, Lee Y, Moon HR, Zhao LX, Lee KM, Jeong LS. Wang T, et al. Among authors: lee y, lee hj, lee km. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4456-9. doi: 10.1016/j.bmcl.2007.06.013. Epub 2007 Jun 8. Bioorg Med Chem Lett. 2007. PMID: 17582766
Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.
Choi HK, Choi S, Lee Y, Kang DW, Ryu H, Maeng HJ, Chung SJ, Pavlyukovets VA, Pearce LV, Toth A, Tran R, Wang Y, Morgan MA, Blumberg PM, Lee J. Choi HK, et al. Among authors: lee y, lee j. Bioorg Med Chem. 2009 Jan 15;17(2):690-8. doi: 10.1016/j.bmc.2008.11.085. Epub 2008 Dec 25. Bioorg Med Chem. 2009. PMID: 19135377 Free PMC article.
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