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Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization.
Müller KH, Hayward R, Rajan R, Whitehead M, Cobb AM, Ahmad S, Sun M, Goldberga I, Li R, Bashtanova U, Puszkarska AM, Reid DG, Brooks RA, Skepper JN, Bordoloi J, Chow WY, Oschkinat H, Groombridge A, Scherman OA, Harrison JA, Verhulst A, D'Haese PC, Neven E, Needham LM, Lee SF, Shanahan CM, Duer MJ. Müller KH, et al. Among authors: lee sf. Cell Rep. 2019 Jun 11;27(11):3124-3138.e13. doi: 10.1016/j.celrep.2019.05.038. Cell Rep. 2019. PMID: 31189100 Free PMC article.
FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.
Basu S, Needham LM, Lando D, Taylor EJR, Wohlfahrt KJ, Shah D, Boucher W, Tan YL, Bates LE, Tkachenko O, Cramard J, Lagerholm BC, Eggeling C, Hendrich B, Klenerman D, Lee SF, Laue ED. Basu S, et al. Among authors: lee sf. Nat Commun. 2018 Jun 28;9(1):2520. doi: 10.1038/s41467-018-04486-0. Nat Commun. 2018. PMID: 29955052 Free PMC article.
Single-molecule visualization of DNA G-quadruplex formation in live cells.
Di Antonio M, Ponjavic A, Radzevičius A, Ranasinghe RT, Catalano M, Zhang X, Shen J, Needham LM, Lee SF, Klenerman D, Balasubramanian S. Di Antonio M, et al. Among authors: lee sf. Nat Chem. 2020 Sep;12(9):832-837. doi: 10.1038/s41557-020-0506-4. Epub 2020 Jul 20. Nat Chem. 2020. PMID: 32690897 Free PMC article.
ThX - a next-generation probe for the early detection of amyloid aggregates.
Needham LM, Weber J, Varela JA, Fyfe JWB, Do DT, Xu CK, Tutton L, Cliffe R, Keenlyside B, Klenerman D, Dobson CM, Hunter CA, Müller KH, O'Holleran K, Bohndiek SE, Snaddon TN, Lee SF. Needham LM, et al. Among authors: lee sf. Chem Sci. 2020 Feb 21;11(18):4578-4583. doi: 10.1039/c9sc04730a. Chem Sci. 2020. PMID: 34122915 Free PMC article.
Single-Molecule Stoichiometry of Supramolecular Complexes.
McLean A, Sala RL, Longbottom BW, Carr AR, McCune JA, Lee SF, Scherman OA. McLean A, et al. Among authors: lee sf. J Am Chem Soc. 2024 May 15;146(19):12877-12882. doi: 10.1021/jacs.4c00611. Epub 2024 May 6. J Am Chem Soc. 2024. PMID: 38710014
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers.
Aprile FA, Sormanni P, Podpolny M, Chhangur S, Needham LM, Ruggeri FS, Perni M, Limbocker R, Heller GT, Sneideris T, Scheidt T, Mannini B, Habchi J, Lee SF, Salinas PC, Knowles TPJ, Dobson CM, Vendruscolo M. Aprile FA, et al. Among authors: lee sf. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13509-13518. doi: 10.1073/pnas.1919464117. Epub 2020 Jun 3. Proc Natl Acad Sci U S A. 2020. PMID: 32493749 Free PMC article.
543 results