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Genetic animal models of cerebral vasculopathies.
Lee JH, Bacskai BJ, Ayata C. Lee JH, et al. Prog Mol Biol Transl Sci. 2012;105:25-55. doi: 10.1016/B978-0-12-394596-9.00002-0. Prog Mol Biol Transl Sci. 2012. PMID: 22137428 Free PMC article. Review.
Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease.
Arboleda-Velasquez JF, Manent J, Lee JH, Tikka S, Ospina C, Vanderburg CR, Frosch MP, Rodríguez-Falcón M, Villen J, Gygi S, Lopera F, Kalimo H, Moskowitz MA, Ayata C, Louvi A, Artavanis-Tsakonas S. Arboleda-Velasquez JF, et al. Among authors: lee jh. Proc Natl Acad Sci U S A. 2011 May 24;108(21):E128-35. doi: 10.1073/pnas.1101964108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555590 Free PMC article.
Migraine mutations increase stroke vulnerability by facilitating ischemic depolarizations.
Eikermann-Haerter K, Lee JH, Yuzawa I, Liu CH, Zhou Z, Shin HK, Zheng Y, Qin T, Kurth T, Waeber C, Ferrari MD, van den Maagdenberg AM, Moskowitz MA, Ayata C. Eikermann-Haerter K, et al. Among authors: lee jh. Circulation. 2012 Jan 17;125(2):335-45. doi: 10.1161/CIRCULATIONAHA.111.045096. Epub 2011 Dec 5. Circulation. 2012. PMID: 22144569 Free PMC article.
Multiparametric, longitudinal optical coherence tomography imaging reveals acute injury and chronic recovery in experimental ischemic stroke.
Srinivasan VJ, Mandeville ET, Can A, Blasi F, Climov M, Daneshmand A, Lee JH, Yu E, Radhakrishnan H, Lo EH, Sakadžić S, Eikermann-Haerter K, Ayata C. Srinivasan VJ, et al. Among authors: lee jh. PLoS One. 2013 Aug 7;8(8):e71478. doi: 10.1371/journal.pone.0071478. Print 2013. PLoS One. 2013. PMID: 23940761 Free PMC article.
Selective ROCK2 Inhibition In Focal Cerebral Ischemia.
Lee JH, Zheng Y, von Bornstadt D, Wei Y, Balcioglu A, Daneshmand A, Yalcin N, Yu E, Herisson F, Atalay YB, Kim MH, Ahn YJ, Balkaya M, Sweetnam P, Schueller O, Poyurovsky MV, Kim HH, Lo EH, Furie KL, Ayata C. Lee JH, et al. Ann Clin Transl Neurol. 2014 Jan 1;1(1):2-14. doi: 10.1002/acn3.19. Ann Clin Transl Neurol. 2014. PMID: 24466563 Free PMC article.
Migraine prophylaxis, ischemic depolarizations, and stroke outcomes in mice.
Eikermann-Haerter K, Lee JH, Yalcin N, Yu ES, Daneshmand A, Wei Y, Zheng Y, Can A, Sengul B, Ferrari MD, van den Maagdenberg AM, Ayata C. Eikermann-Haerter K, et al. Among authors: lee jh. Stroke. 2015 Jan;46(1):229-36. doi: 10.1161/STROKEAHA.114.006982. Epub 2014 Nov 25. Stroke. 2015. PMID: 25424478 Free PMC article.
CADASIL mutations sensitize the brain to ischemia via spreading depolarizations and abnormal extracellular potassium homeostasis.
Oka F, Lee JH, Yuzawa I, Li M, von Bornstaedt D, Eikermann-Haerter K, Qin T, Chung DY, Sadeghian H, Seidel JL, Imai T, Vuralli D, Platt RM, Nelson MT, Joutel A, Sakadzic S, Ayata C. Oka F, et al. Among authors: lee jh. J Clin Invest. 2022 Apr 15;132(8):e149759. doi: 10.1172/JCI149759. J Clin Invest. 2022. PMID: 35202003 Free PMC article.
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