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Solid lipid nanoparticles self-assembled from spray dried microparticles.
Sanchez-Vazquez B, Lee JB, Strimaite M, Buanz A, Bailey R, Gershkovich P, Pasparakis G, Williams GR. Sanchez-Vazquez B, et al. Among authors: lee jb. Int J Pharm. 2019 Dec 15;572:118784. doi: 10.1016/j.ijpharm.2019.118784. Epub 2019 Oct 30. Int J Pharm. 2019. PMID: 31676339
Inclusion of Medium-Chain Triglyceride in Lipid-Based Formulation of Cannabidiol Facilitates Micellar Solubilization In Vitro, but In Vivo Performance Remains Superior with Pure Sesame Oil Vehicle.
Feng W, Qin C, Cipolla E, Lee JB, Zgair A, Chu Y, Ortori CA, Stocks MJ, Constantinescu CS, Barrett DA, Fischer PM, Gershkovich P. Feng W, et al. Among authors: lee jb. Pharmaceutics. 2021 Aug 27;13(9):1349. doi: 10.3390/pharmaceutics13091349. Pharmaceutics. 2021. PMID: 34575426 Free PMC article.
Natural sesame oil is superior to pre-digested lipid formulations and purified triglycerides in promoting the intestinal lymphatic transport and systemic bioavailability of cannabidiol.
Feng W, Qin C, Chu Y, Berton M, Lee JB, Zgair A, Bettonte S, Stocks MJ, Constantinescu CS, Barrett DA, Fischer PM, Gershkovich P. Feng W, et al. Among authors: lee jb. Eur J Pharm Biopharm. 2021 May;162:43-49. doi: 10.1016/j.ejpb.2021.02.013. Epub 2021 Mar 5. Eur J Pharm Biopharm. 2021. PMID: 33677067
Administration in fed state but not controlled release in the colon increases oral bioavailability of DF030263, a promising drug candidate for chronic lymphocytic leukemia.
Lee JB, Zang X, Zgair A, Ooi TQ, Foley DW, Voronin G, Kagan L, Soukarieh F, Gao R, Shao H, Soh WT, Kim TH, Kim MG, Yun HY, Wilson AJ, Fischer PM, Gershkovich P. Lee JB, et al. Eur J Pharm Biopharm. 2021 Aug;165:106-112. doi: 10.1016/j.ejpb.2021.05.006. Epub 2021 May 12. Eur J Pharm Biopharm. 2021. PMID: 33991611
Codrug Approach for the Potential Treatment of EML4-ALK Positive Lung Cancer.
Garces AE, Al-Hayali M, Lee JB, Li J, Gershkovich P, Bradshaw TD, Stocks MJ. Garces AE, et al. Among authors: lee jb. ACS Med Chem Lett. 2019 Sep 27;11(3):316-321. doi: 10.1021/acsmedchemlett.9b00378. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184963 Free PMC article.
2,224 results