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Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies.
Linciano P, Nasti R, Listro R, Amadio M, Pascale A, Potenza D, Vasile F, Minneci M, Ann J, Lee J, Zhou X, Mitchell GA, Blumberg PM, Rossi D, Collina S. Linciano P, et al. Among authors: lee j. Chirality. 2022 Mar;34(3):498-513. doi: 10.1002/chir.23406. Epub 2021 Dec 28. Chirality. 2022. PMID: 34962318
High affinity antagonists of the vanilloid receptor.
Wang Y, Szabo T, Welter JD, Toth A, Tran R, Lee J, Kang SU, Suh YG, Blumberg PM, Lee J. Wang Y, et al. Among authors: lee j. Mol Pharmacol. 2002 Oct;62(4):947-56. doi: 10.1124/mol.62.4.947. Mol Pharmacol. 2002. PMID: 12237342
Conformationally constrained analogues of diacylglycerol. 19. Synthesis and protein kinase C binding affinity of diacylglycerol lactones bearing an N-hydroxylamide side chain.
Choi Y, Kang JH, Lewin NE, Blumberg PM, Lee J, Marquez VE. Choi Y, et al. Among authors: lee j. J Med Chem. 2003 Jun 19;46(13):2790-3. doi: 10.1021/jm030082c. J Med Chem. 2003. PMID: 12801241
The structures of N-hydroxylamides 1a and 1b, previously reported by Lee et al. in J. Med. Chem. 2001, 44, 4309-4312 as strong protein kinase C (PK-C) ligands, were incorrect and correspond instead to esters 2a and 2b, respectively. ...
The structures of N-hydroxylamides 1a and 1b, previously reported by Lee et al. in J. Med. Chem. 2001, 44, 4309-4312 as strong …
High-affinity partial agonists of the vanilloid receptor.
Wang Y, Toth A, Tran R, Szabo T, Welter JD, Blumberg PM, Lee J, Kang SU, Lim JO, Lee J. Wang Y, et al. Among authors: lee j. Mol Pharmacol. 2003 Aug;64(2):325-33. doi: 10.1124/mol.64.2.325. Mol Pharmacol. 2003. PMID: 12869637
Analysis of structure-activity relationships for the 'B-region' of N-(3-acyloxy-2-benzylpropyl)-N(')-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: discovery of an N-hydroxythiourea analogue with potent analgesic activity.
Lee J, Kang SU, Choi HK, Lee J, Lim JO, Kil MJ, Jin MK, Kim KP, Sung JH, Chung SJ, Ha HJ, Kim YH, Pearce LV, Tran R, Lundberg DJ, Wang Y, Toth A, Blumberg PM. Lee J, et al. Bioorg Med Chem Lett. 2004 May 3;14(9):2291-7. doi: 10.1016/j.bmcl.2004.02.002. Bioorg Med Chem Lett. 2004. PMID: 15081027
141,855 results
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