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Chain-branched 1,3-dibenzylthioureas as vanilloid receptor 1 antagonists.
Ryu CH, Jang MJ, Jung JW, Park JH, Choi HY, Suh YG, Oh U, Park HG, Lee J, Koh HJ, Mo JH, Joo YH, Park YH, Kim HD. Ryu CH, et al. Among authors: lee j. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1751-5. doi: 10.1016/j.bmcl.2004.01.066. Bioorg Med Chem Lett. 2004. PMID: 15026064
Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists.
Lee J, Jin MK, Kang SU, Kim SY, Lee J, Shin M, Hwang J, Cho S, Choi YS, Choi HK, Kim SE, Suh YG, Lee YS, Kim YH, Ha HJ, Toth A, Pearce LV, Tran R, Szabo T, Welter JD, Lundberg DJ, Wang Y, Lazar J, Pavlyukovets VA, Morgan MA, Blumberg PM. Lee J, et al. Among authors: lee ys. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4143-50. doi: 10.1016/j.bmcl.2005.06.006. Bioorg Med Chem Lett. 2005. PMID: 15993063
Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists.
Lee J, Kang SU, Kil MJ, Shin M, Lim JO, Choi HK, Jin MK, Kim SY, Kim SE, Lee YS, Min KH, Kim YH, Ha HJ, Tran R, Welter JD, Wang Y, Szabo T, Pearce LV, Lundberg DJ, Toth A, Pavlyukovets VA, Morgan MA, Blumberg PM. Lee J, et al. Among authors: lee ys. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4136-42. doi: 10.1016/j.bmcl.2005.06.009. Bioorg Med Chem Lett. 2005. PMID: 16005215
Novel potent antagonists of transient receptor potential channel, vanilloid subfamily member 1: structure-activity relationship of 1,3-diarylalkyl thioureas possessing new vanilloid equivalents.
Suh YG, Lee YS, Min KH, Park OH, Kim JK, Seung HS, Seo SY, Lee BY, Nam YH, Lee KO, Kim HD, Park HG, Lee J, Oh U, Lim JO, Kang SU, Kil MJ, Koo JY, Shin SS, Joo YH, Kim JK, Jeong YS, Kim SY, Park YH. Suh YG, et al. Among authors: lee ko, lee by, lee ys, lee j. J Med Chem. 2005 Sep 8;48(18):5823-36. doi: 10.1021/jm0502790. J Med Chem. 2005. PMID: 16134949
Alpha-substituted N-(4-tert-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as potent and stereospecific TRPV1 antagonists.
Chung JU, Kim SY, Lim JO, Choi HK, Kang SU, Yoon HS, Ryu H, Kang DW, Lee J, Kang B, Choi S, Toth A, Pearce LV, Pavlyukovets VA, Lundberg DJ, Blumberg PM. Chung JU, et al. Among authors: lee j. Bioorg Med Chem. 2007 Sep 15;15(18):6043-53. doi: 10.1016/j.bmc.2007.06.041. Epub 2007 Jun 26. Bioorg Med Chem. 2007. PMID: 17629487
Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.
Choi HK, Choi S, Lee Y, Kang DW, Ryu H, Maeng HJ, Chung SJ, Pavlyukovets VA, Pearce LV, Toth A, Tran R, Wang Y, Morgan MA, Blumberg PM, Lee J. Choi HK, et al. Among authors: lee y, lee j. Bioorg Med Chem. 2009 Jan 15;17(2):690-8. doi: 10.1016/j.bmc.2008.11.085. Epub 2008 Dec 25. Bioorg Med Chem. 2009. PMID: 19135377 Free PMC article.
N-4-t-Butylbenzyl 2-(4-methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure-activity relationships in the A-region.
Kim YS, Kil MJ, Kang SU, Ryu H, Kim MS, Cho Y, Bhondwe RS, Thorat SA, Sun W, Liu K, Lee JH, Choi S, Pearce LV, Pavlyukovets VA, Morgan MA, Tran R, Lazar J, Blumberg PM, Lee J. Kim YS, et al. Among authors: lee j, lee jh. Bioorg Med Chem. 2012 Jan 1;20(1):215-24. doi: 10.1016/j.bmc.2011.11.008. Epub 2011 Nov 22. Bioorg Med Chem. 2012. PMID: 22169633 Free PMC article.
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