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2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists.
Ryu H, Seo S, Cho SH, Kim HS, Jung A, Kang DW, Son K, Cui M, Hong SH, Sharma PK, Choi S, Blumberg PM, Frank-Foltyn R, Bahrenberg G, Stockhausen H, Schiene K, Christoph T, Frormann S, Lee J. Ryu H, et al. Among authors: lee j. Bioorg Med Chem Lett. 2014 Aug 15;24(16):4039-43. doi: 10.1016/j.bmcl.2014.05.074. Epub 2014 Jun 2. Bioorg Med Chem Lett. 2014. PMID: 24948568 Free PMC article.
High affinity antagonists of the vanilloid receptor.
Wang Y, Szabo T, Welter JD, Toth A, Tran R, Lee J, Kang SU, Suh YG, Blumberg PM, Lee J. Wang Y, et al. Among authors: lee j. Mol Pharmacol. 2002 Oct;62(4):947-56. doi: 10.1124/mol.62.4.947. Mol Pharmacol. 2002. PMID: 12237342
Conformationally constrained analogues of diacylglycerol. 19. Synthesis and protein kinase C binding affinity of diacylglycerol lactones bearing an N-hydroxylamide side chain.
Choi Y, Kang JH, Lewin NE, Blumberg PM, Lee J, Marquez VE. Choi Y, et al. Among authors: lee j. J Med Chem. 2003 Jun 19;46(13):2790-3. doi: 10.1021/jm030082c. J Med Chem. 2003. PMID: 12801241
The structures of N-hydroxylamides 1a and 1b, previously reported by Lee et al. in J. Med. Chem. 2001, 44, 4309-4312 as strong protein kinase C (PK-C) ligands, were incorrect and correspond instead to esters 2a and 2b, respectively. ...
The structures of N-hydroxylamides 1a and 1b, previously reported by Lee et al. in J. Med. Chem. 2001, 44, 4309-4312 as strong …
N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.
Lee J, Lee J, Kang M, Shin M, Kim JM, Kang SU, Lim JO, Choi HK, Suh YG, Park HG, Oh U, Kim HD, Park YH, Ha HJ, Kim YH, Toth A, Wang Y, Tran R, Pearce LV, Lundberg DJ, Blumberg PM. Lee J, et al. J Med Chem. 2003 Jul 3;46(14):3116-26. doi: 10.1021/jm030089u. J Med Chem. 2003. PMID: 12825950
High-affinity partial agonists of the vanilloid receptor.
Wang Y, Toth A, Tran R, Szabo T, Welter JD, Blumberg PM, Lee J, Kang SU, Lim JO, Lee J. Wang Y, et al. Among authors: lee j. Mol Pharmacol. 2003 Aug;64(2):325-33. doi: 10.1124/mol.64.2.325. Mol Pharmacol. 2003. PMID: 12869637
141,798 results
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