Lee CH - Search Results

1

The differential vulnerabilities of Per2 knockout mice to the addictive properties of methamphetamine and cocaine.

Sayson LV, Lee HJ, Ortiz DM, Kim M, Custodio RJP, Lee CH, Lee YS, Cheong JH, Kim HJ. Sayson LV, et al. Among authors: lee ch, lee ys, lee hj. Prog Neuropsychopharmacol Biol Psychiatry. 2023 Aug 30;126:110782. doi: 10.1016/j.pnpbp.2023.110782. Epub 2023 May 2. Prog Neuropsychopharmacol Biol Psychiatry. 2023. PMID: 37141987

2

Bestatin analogs-4-quinolinone hybrids as antileishmanial hits: Design, repurposing rational, synthesis, in vitro and in silico studies.

Hassan AHE, Mahmoud K, Phan TN, Shaldam MA, Lee CH, Kim YJ, Cho SB, Bayoumi WA, El-Sayed SM, Choi Y, Moon S, No JH, Lee YS. Hassan AHE, et al. Among authors: lee ch, lee ys. Eur J Med Chem. 2023 Mar 15;250:115211. doi: 10.1016/j.ejmech.2023.115211. Epub 2023 Feb 14. Eur J Med Chem. 2023. PMID: 36827952

3

Design, synthesis, and repurposing of O⁶-aminoalkyl-sulfuretin analogs towards discovery of potential lead compounds as antileishmanial agents.

Hassan AHE, Phan TN, Moon S, Lee CH, Kim YJ, Cho SB, El-Sayed SM, Choi Y, No JH, Lee YS. Hassan AHE, et al. Among authors: lee ch, lee ys. Eur J Med Chem. 2023 May 5;251:115256. doi: 10.1016/j.ejmech.2023.115256. Epub 2023 Mar 9. Eur J Med Chem. 2023. PMID: 36944273

4

Deletion of Cryab increases the vulnerability of mice to the addiction-like effects of the cannabinoid JWH-018 via upregulation of striatal NF-κB expression.

Sayson LV, Ortiz DM, Lee HJ, Kim M, Custodio RJP, Yun J, Lee CH, Lee YS, Cha HJ, Cheong JH, Kim HJ. Sayson LV, et al. Among authors: lee ch, lee ys, lee hj. Front Pharmacol. 2023 Mar 16;14:1135929. doi: 10.3389/fphar.2023.1135929. eCollection 2023. Front Pharmacol. 2023. PMID: 37007015 Free PMC article.

5

Scaffold hopping of N-benzyl-3,4,5-trimethoxyaniline: 5,6,7-Trimethoxyflavan derivatives as novel potential anticancer agents modulating hippo signaling pathway.

Hassan AHE, Wang CY, Lee HJ, Jung SJ, Kim YJ, Cho SB, Lee CH, Ham G, Oh T, Lee SK, Lee YS. Hassan AHE, et al. Among authors: lee ch, lee sk, lee ys, lee hj. Eur J Med Chem. 2023 Aug 5;256:115421. doi: 10.1016/j.ejmech.2023.115421. Epub 2023 Apr 26. Eur J Med Chem. 2023. PMID: 37163949

6

Synthesis and Biological Evaluation of O⁶-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases.

Hassan AHE, Kim HJ, Park K, Choi Y, Moon S, Lee CH, Kim YJ, Cho SB, Gee MS, Lee D, Park JH, Lee JK, Ryu JH, Park KD, Lee YS. Hassan AHE, et al. Among authors: lee ch, lee d, lee ys, lee jk. Antioxidants (Basel). 2023 Apr 29;12(5):1033. doi: 10.3390/antiox12051033. Antioxidants (Basel). 2023. PMID: 37237899 Free PMC article.

7

Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase.

Hassan AHE, Oh YI, Lee CH, Kim YJ, Cho SB, Alam MM, Park SE, Chung KS, Lee KT, Lee YS. Hassan AHE, et al. Among authors: lee ch, lee kt, lee ys. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2217695. doi: 10.1080/14756366.2023.2217695. J Enzyme Inhib Med Chem. 2023. PMID: 37246947 Free PMC article.

8

Rational repurposing, synthesis, in vitro and in silico studies of chromone-peptidyl hybrids as potential agents against Leishmania donovani.

Hassan AHE, Bayoumi WA, El-Sayed SM, Phan TN, Kim YJ, Lee CH, Cho SB, Oh T, Ham G, Mahmoud K, No JH, Lee YS. Hassan AHE, et al. Among authors: lee ch, lee ys. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2229071. doi: 10.1080/14756366.2023.2229071. J Enzyme Inhib Med Chem. 2023. PMID: 37381756 Free PMC article.

9

Repurposing of conformationally-restricted cyclopentane-based AKT-inhibitors leads to discovery of potential and more selective antileishmanial agents than miltefosine.

Hassan AHE, Alam MM, Phan TN, Baek KH, Lee H, Cho SB, Lee CH, Kim YJ, No JH, Lee YS. Hassan AHE, et al. Among authors: lee ch, lee h, lee ys. Bioorg Chem. 2023 Dec;141:106890. doi: 10.1016/j.bioorg.2023.106890. Epub 2023 Sep 27. Bioorg Chem. 2023. PMID: 37783099

10

Repurposing Synthetic Congeners of a Natural Product Aurone Unveils a Lead Antitumor Agent Inhibiting Folded P-Loop Conformation of MET Receptor Tyrosine Kinase.

Hassan AHE, Wang CY, Lee CJ, Jeon HR, Choi Y, Moon S, Lee CH, Kim YJ, Cho SB, Mahmoud K, El-Sayed SM, Lee SK, Lee YS. Hassan AHE, et al. Among authors: lee ch, lee cj, lee sk, lee ys. Pharmaceuticals (Basel). 2023 Nov 13;16(11):1597. doi: 10.3390/ph16111597. Pharmaceuticals (Basel). 2023. PMID: 38004462 Free PMC article.

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