Lee AY - Search Results

1

Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1-mediated immunoescape via STING-IFN signaling and extracellular vesicles.

Cheng AN, Cheng LC, Kuo CL, Lo YK, Chou HY, Chen CH, Wang YH, Chuang TH, Cheng SJ, Lee AY. Cheng AN, et al. Among authors: lee ay. J Immunother Cancer. 2020 Dec;8(2):e001372. doi: 10.1136/jitc-2020-001372. J Immunother Cancer. 2020. PMID: 33268351 Free PMC article.

2

Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.

Lee AY, Chiba T, Truong LN, Cheng AN, Do J, Cho MJ, Chen L, Wu X. Lee AY, et al. J Biol Chem. 2012 Jan 20;287(4):2531-43. doi: 10.1074/jbc.M111.291104. Epub 2011 Nov 28. J Biol Chem. 2012. PMID: 22123827 Free PMC article.

3

Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents.

Cheng AN, Jiang SS, Fan CC, Lo YK, Kuo CY, Chen CH, Liu YL, Lee CC, Chen WS, Huang TS, Wang TY, Lee AY. Cheng AN, et al. Among authors: lee ay, lee cc. Cancer Lett. 2013 Sep 1;337(2):218-25. doi: 10.1016/j.canlet.2013.05.008. Epub 2013 May 16. Cancer Lett. 2013. PMID: 23684929

4

Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma.

Fang WT, Fan CC, Li SM, Jang TH, Lin HP, Shih NY, Chen CH, Wang TY, Huang SF, Lee AY, Liu YL, Tsai FY, Huang CT, Yang SJ, Yen LJ, Chuu CP, Chen CY, Hsiung CA, Chang JY, Wang LH, Chang IS, Jiang SS. Fang WT, et al. Among authors: lee ay. Int J Cancer. 2014 Aug 15;135(4):809-19. doi: 10.1002/ijc.28734. Epub 2014 Jan 30. Int J Cancer. 2014. PMID: 24477565 Free article.

5

Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma.

Cheng CW, Hsiao JR, Fan CC, Lo YK, Tzen CY, Wu LW, Fang WY, Cheng AJ, Chen CH, Chang IS, Jiang SS, Chang JY, Lee AY. Cheng CW, et al. Among authors: lee ay. Mol Carcinog. 2016 May;55(5):499-513. doi: 10.1002/mc.22297. Epub 2015 Mar 1. Mol Carcinog. 2016. PMID: 25728212

6

Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer.

Cheng AN, Fan CC, Lo YK, Kuo CL, Wang HC, Lien IH, Lin SY, Chen CH, Jiang SS, Chang IS, Juan HF, Lyu PC, Lee AY. Cheng AN, et al. Among authors: lee ay. Sci Rep. 2017 Dec 5;7(1):17024. doi: 10.1038/s41598-017-17126-2. Sci Rep. 2017. PMID: 29209046 Free PMC article.

7

Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity.

Sung YJ, Kao TY, Kuo CL, Fan CC, Cheng AN, Fang WC, Chou HY, Lo YK, Chen CH, Jiang SS, Chang IS, Hsu CH, Lee JC, Lee AY. Sung YJ, et al. Among authors: lee jc, lee ay. Cell Death Dis. 2018 Jun 13;9(6):697. doi: 10.1038/s41419-018-0730-7. Cell Death Dis. 2018. PMID: 29899330 Free PMC article.

8

USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation.

Lu CH, Yeh DW, Lai CY, Liu YL, Huang LR, Lee AY, Jin SC, Chuang TH. Lu CH, et al. Among authors: lee ay. Oncogene. 2018 Dec;37(49):6327-6340. doi: 10.1038/s41388-018-0411-0. Epub 2018 Jul 23. Oncogene. 2018. PMID: 30038267 Free PMC article.

9

Identification of Novel Cdc7 Kinase Inhibitors as Anti-Cancer Agents that Target the Interaction with Dbf4 by the Fragment Complementation and Drug Repositioning Approach.

Cheng AN, Lo YK, Lin YS, Tang TK, Hsu CH, Hsu JT, Lee AY. Cheng AN, et al. Among authors: lee ay. EBioMedicine. 2018 Oct;36:241-251. doi: 10.1016/j.ebiom.2018.09.030. Epub 2018 Oct 5. EBioMedicine. 2018. PMID: 30293817 Free PMC article.

10

AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells.

Cheng LC, Chen YL, Cheng AN, Lee AY, Cho CY, Huang JS, Chuang SE. Cheng LC, et al. Among authors: lee ay. J Biomed Sci. 2018 Nov 12;25(1):80. doi: 10.1186/s12929-018-0465-x. J Biomed Sci. 2018. PMID: 30419905 Free PMC article.

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