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Page 1
Establishment of Pancreatic Cancer-Derived Tumor Organoids and Fibroblasts From Fresh Tissue.
Díaz-Alejo JF, April-Monn S, Cihova M, Buocikova V, Villalón López J, Urbanova M, Lechuga CG, Tomas M, Dubovan P, Sánchez BL, Páez SC, Sanjuanbenito A, Lobo E, Romio de la Heras E, Guerra C, de la Pinta C, Barreto Melian E, Rodríguez Garrote M, Carrato A, Ruiz-Cañas L, Sainz B Jr, Torres A, Smolkova B, Earl J. Díaz-Alejo JF, et al. Among authors: lechuga cg. J Vis Exp. 2023 May 26;(195). doi: 10.3791/65229. J Vis Exp. 2023. PMID: 37306424
Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas.
Salmón M, Álvarez-Díaz R, Fustero-Torre C, Brehey O, Lechuga CG, Sanclemente M, Fernández-García F, López-García A, Martín-Guijarro MC, Rodríguez-Perales S, Bousquet-Mur E, Morales-Cacho L, Mulero F, Al-Shahrour F, Martínez L, Domínguez O, Caleiras E, Ortega S, Guerra C, Musteanu M, Drosten M, Barbacid M. Salmón M, et al. Among authors: lechuga cg. J Clin Invest. 2023 Apr 3;133(7):e164413. doi: 10.1172/JCI164413. J Clin Invest. 2023. PMID: 36928090 Free PMC article.
Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation.
García-Alonso S, Mesa P, Ovejero LP, Aizpurua G, Lechuga CG, Zarzuela E, Santiveri CM, Sanclemente M, Muñoz J, Musteanu M, Campos-Olivas R, Martínez-Torrecuadrada J, Barbacid M, Montoya G. García-Alonso S, et al. Among authors: lechuga cg. Mol Cell. 2022 Sep 15;82(18):3438-3452.e8. doi: 10.1016/j.molcel.2022.08.012. Epub 2022 Sep 1. Mol Cell. 2022. PMID: 36055235 Free article.
KRAS4A induces metastatic lung adenocarcinomas in vivo in the absence of the KRAS4B isoform.
Salmón M, Paniagua G, Lechuga CG, Fernández-García F, Zarzuela E, Álvarez-Díaz R, Musteanu M, Guerra C, Caleiras E, Muñoz J, Ortega S, Drosten M, Barbacid M. Salmón M, et al. Among authors: lechuga cg. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2023112118. doi: 10.1073/pnas.2023112118. Proc Natl Acad Sci U S A. 2021. PMID: 34301865 Free PMC article.
Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF.
Blasco MT, Navas C, Martín-Serrano G, Graña-Castro O, Lechuga CG, Martín-Díaz L, Djurec M, Li J, Morales-Cacho L, Esteban-Burgos L, Perales-Patón J, Bousquet-Mur E, Castellano E, Jacob HKC, Cabras L, Musteanu M, Drosten M, Ortega S, Mulero F, Sainz B Jr, Dusetti N, Iovanna J, Sánchez-Bueno F, Hidalgo M, Khiabanian H, Rabadán R, Al-Shahrour F, Guerra C, Barbacid M. Blasco MT, et al. Among authors: lechuga cg. Cancer Cell. 2019 Apr 15;35(4):573-587.e6. doi: 10.1016/j.ccell.2019.03.002. Epub 2019 Apr 8. Cancer Cell. 2019. PMID: 30975481 Free PMC article.
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