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Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.
Begus-Nahrmann Y, Hartmann D, Kraus J, Eshraghi P, Scheffold A, Grieb M, Rasche V, Schirmacher P, Lee HW, Kestler HA, Lechel A, Rudolph KL. Begus-Nahrmann Y, et al. Among authors: lechel a. J Clin Invest. 2021 Jan 4;131(1):e145852. doi: 10.1172/JCI145852. J Clin Invest. 2021. PMID: 33393513 Free PMC article. No abstract available.
Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure.
Armacki M, Trugenberger AK, Ellwanger AK, Eiseler T, Schwerdt C, Bettac L, Langgartner D, Azoitei N, Halbgebauer R, Groß R, Barth T, Lechel A, Walter BM, Kraus JM, Wiegreffe C, Grimm J, Scheffold A, Schneider MR, Peuker K, Zeißig S, Britsch S, Rose-John S, Vettorazzi S, Wolf E, Tannapfel A, Steinestel K, Reber SO, Walther P, Kestler HA, Radermacher P, Barth TF, Huber-Lang M, Kleger A, Seufferlein T. Armacki M, et al. Among authors: lechel a. J Clin Invest. 2018 Nov 1;128(11):5056-5072. doi: 10.1172/JCI97912. Epub 2018 Oct 15. J Clin Invest. 2018. PMID: 30320600 Free PMC article.
Author Correction: Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction.
Sperka T, Song Z, Morita Y, Nalapareddy K, Guachalla LM, Lechel A, Begus-Nahrmann Y, Burkhalter MD, Mach M, Schlaudraff F, Liss B, Ju Z, Speicher MR, Rudolph KL. Sperka T, et al. Among authors: lechel a. Nat Cell Biol. 2021 Mar;23(3):292. doi: 10.1038/s41556-021-00633-w. Nat Cell Biol. 2021. PMID: 33510409 No abstract available.
69 results