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YAP Activation Drives Liver Regeneration after Cholestatic Damage Induced by Rbpj Deletion.
Tharehalli U, Svinarenko M, Kraus JM, Kühlwein SD, Szekely R, Kiesle U, Scheffold A, Barth TFE, Kleger A, Schirmbeck R, Kestler HA, Seufferlein T, Oswald F, Katz SF, Lechel A. Tharehalli U, et al. Among authors: lechel a. Int J Mol Sci. 2018 Nov 29;19(12):3801. doi: 10.3390/ijms19123801. Int J Mol Sci. 2018. PMID: 30501048 Free PMC article.
Telomerase gene mutations are associated with cirrhosis formation.
Hartmann D, Srivastava U, Thaler M, Kleinhans KN, N'kontchou G, Scheffold A, Bauer K, Kratzer RF, Kloos N, Katz SF, Song Z, Begus-Nahrmann Y, Kleger A, von Figura G, Strnad P, Lechel A, Günes C, Potthoff A, Deterding K, Wedemeyer H, Ju Z, Song G, Xiao F, Gillen S, Schrezenmeier H, Mertens T, Ziol M, Friess H, Jarek M, Manns MP, Beaugrand M, Rudolph KL. Hartmann D, et al. Among authors: lechel a. Hepatology. 2011 May;53(5):1608-17. doi: 10.1002/hep.24217. Hepatology. 2011. PMID: 21520174
Increased reprogramming capacity of mouse liver progenitor cells, compared with differentiated liver cells, requires the BAF complex.
Kleger A, Mahaddalkar PU, Katz SF, Lechel A, Joo JY, Loya K, Lin Q, Hartmann D, Liebau S, Kraus JM, Cantz T, Kestler HA, Zaehres H, Schöler H, Rudolph KL. Kleger A, et al. Among authors: lechel a. Gastroenterology. 2012 Apr;142(4):907-17. doi: 10.1053/j.gastro.2012.01.004. Epub 2012 Jan 12. Gastroenterology. 2012. PMID: 22245845
A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage.
Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wuestefeld T, Dauch D, Schrezenmeier H, Hofmann WK, Nakauchi H, Ju Z, Kestler HA, Zender L, Rudolph KL. Wang J, et al. Among authors: lechel a. Cell. 2012 Mar 2;148(5):1001-14. doi: 10.1016/j.cell.2012.01.040. Cell. 2012. PMID: 22385964 Free article.
Telomere length in mantle cell lymphoma.
Jebaraj BM, Kienle D, Lechel A, Mertens D, Heuberger M, Ott G, Rosenwald A, Barth TF, Möller P, Zenz T, Döhner H, Stilgenbauer S. Jebaraj BM, et al. Among authors: lechel a. Blood. 2013 Feb 14;121(7):1184-7. doi: 10.1182/blood-2012-08-452649. Epub 2012 Dec 14. Blood. 2013. PMID: 23243283 Free article.
p21 promotes sustained liver regeneration and hepatocarcinogenesis in chronic cholestatic liver injury.
Marhenke S, Buitrago-Molina LE, Endig J, Orlik J, Schweitzer N, Klett S, Longerich T, Geffers R, Sánchez Muñoz A, Dorrell C, Katz SF, Lechel A, Weng H, Krech T, Lehmann U, Dooley S, Rudolph KL, Manns MP, Vogel A. Marhenke S, et al. Among authors: lechel a. Gut. 2014 Sep;63(9):1501-12. doi: 10.1136/gutjnl-2013-304829. Epub 2013 Oct 3. Gut. 2014. PMID: 24092862
69 results