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Tominersen in Adults with Manifest Huntington's Disease.
McColgan P, Thobhani A, Boak L, Schobel SA, Nicotra A, Palermo G, Trundell D, Zhou J, Schlegel V, Sanwald Ducray P, Hawellek DJ, Dorn J, Simillion C, Lindemann M, Wheelock V, Durr A, Anderson KE, Long JD, Wild EJ, Landwehrmeyer GB, Leavitt BR, Tabrizi SJ, Doody R; GENERATION HD1 Investigators. McColgan P, et al. Among authors: leavitt br. N Engl J Med. 2023 Dec 7;389(23):2203-2205. doi: 10.1056/NEJMc2300400. N Engl J Med. 2023. PMID: 38055260 No abstract available.
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Björkqvist M, Wild EJ, Thiele J, Silvestroni A, Andre R, Lahiri N, Raibon E, Lee RV, Benn CL, Soulet D, Magnusson A, Woodman B, Landles C, Pouladi MA, Hayden MR, Khalili-Shirazi A, Lowdell MW, Brundin P, Bates GP, Leavitt BR, Möller T, Tabrizi SJ. Björkqvist M, et al. Among authors: leavitt br. J Exp Med. 2008 Aug 4;205(8):1869-77. doi: 10.1084/jem.20080178. Epub 2008 Jul 14. J Exp Med. 2008. PMID: 18625748 Free PMC article.
Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data.
Tabrizi SJ, Langbehn DR, Leavitt BR, Roos RA, Durr A, Craufurd D, Kennard C, Hicks SL, Fox NC, Scahill RI, Borowsky B, Tobin AJ, Rosas HD, Johnson H, Reilmann R, Landwehrmeyer B, Stout JC; TRACK-HD investigators. Tabrizi SJ, et al. Among authors: leavitt br. Lancet Neurol. 2009 Sep;8(9):791-801. doi: 10.1016/S1474-4422(09)70170-X. Epub 2009 Jul 29. Lancet Neurol. 2009. PMID: 19646924 Free PMC article. Clinical Trial.
Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis.
Tabrizi SJ, Scahill RI, Durr A, Roos RA, Leavitt BR, Jones R, Landwehrmeyer GB, Fox NC, Johnson H, Hicks SL, Kennard C, Craufurd D, Frost C, Langbehn DR, Reilmann R, Stout JC; TRACK-HD Investigators. Tabrizi SJ, et al. Among authors: leavitt br. Lancet Neurol. 2011 Jan;10(1):31-42. doi: 10.1016/S1474-4422(10)70276-3. Epub 2010 Dec 2. Lancet Neurol. 2011. PMID: 21130037
Development of biomarkers for Huntington's disease.
Weir DW, Sturrock A, Leavitt BR. Weir DW, et al. Among authors: leavitt br. Lancet Neurol. 2011 Jun;10(6):573-90. doi: 10.1016/S1474-4422(11)70070-9. Lancet Neurol. 2011. PMID: 21601164 Review.
Clinical impairment in premanifest and early Huntington's disease is associated with regionally specific atrophy.
Scahill RI, Hobbs NZ, Say MJ, Bechtel N, Henley SM, Hyare H, Langbehn DR, Jones R, Leavitt BR, Roos RA, Durr A, Johnson H, Lehéricy S, Craufurd D, Kennard C, Hicks SL, Stout JC, Reilmann R, Tabrizi SJ; TRACK-HD investigators. Scahill RI, et al. Among authors: leavitt br. Hum Brain Mapp. 2013 Mar;34(3):519-29. doi: 10.1002/hbm.21449. Epub 2011 Nov 18. Hum Brain Mapp. 2013. PMID: 22102212 Free PMC article.
8OHdG as a marker for Huntington disease progression.
Long JD, Matson WR, Juhl AR, Leavitt BR, Paulsen JS; PREDICT-HD Investigators and Coordinators of the Huntington Study Group. Long JD, et al. Among authors: leavitt br. Neurobiol Dis. 2012 Jun;46(3):625-34. doi: 10.1016/j.nbd.2012.02.012. Epub 2012 Mar 5. Neurobiol Dis. 2012. PMID: 22414782 Free PMC article.
215 results