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Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity.
Joas S, Parrish EH, Gnanadurai CW, Lump E, Stürzel CM, Parrish NF, Learn GH, Sauermann U, Neumann B, Rensing KM, Fuchs D, Billingsley JM, Bosinger SE, Silvestri G, Apetrei C, Huot N, Garcia-Tellez T, Müller-Trutwin M, Hotter D, Sauter D, Stahl-Hennig C, Hahn BH, Kirchhoff F. Joas S, et al. Among authors: learn gh. Nat Commun. 2018 Apr 10;9(1):1371. doi: 10.1038/s41467-018-03762-3. Nat Commun. 2018. PMID: 29636452 Free PMC article.
Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.
Sauter D, Schindler M, Specht A, Landford WN, Münch J, Kim KA, Votteler J, Schubert U, Bibollet-Ruche F, Keele BF, Takehisa J, Ogando Y, Ochsenbauer C, Kappes JC, Ayouba A, Peeters M, Learn GH, Shaw G, Sharp PM, Bieniasz P, Hahn BH, Hatziioannou T, Kirchhoff F. Sauter D, et al. Among authors: learn gh. Cell Host Microbe. 2009 Nov 19;6(5):409-21. doi: 10.1016/j.chom.2009.10.004. Cell Host Microbe. 2009. PMID: 19917496 Free PMC article.
Genetic identity and biological phenotype of a transmitted/founder virus representative of nonpathogenic simian immunodeficiency virus infection in African green monkeys.
Gnanadurai CW, Pandrea I, Parrish NF, Kraus MH, Learn GH, Salazar MG, Sauermann U, Töpfer K, Gautam R, Münch J, Stahl-Hennig C, Apetrei C, Hahn BH, Kirchhoff F. Gnanadurai CW, et al. Among authors: learn gh. J Virol. 2010 Dec;84(23):12245-54. doi: 10.1128/JVI.01603-10. Epub 2010 Sep 29. J Virol. 2010. PMID: 20881048 Free PMC article.
Nef proteins of epidemic HIV-1 group O strains antagonize human tetherin.
Kluge SF, Mack K, Iyer SS, Pujol FM, Heigele A, Learn GH, Usmani SM, Sauter D, Joas S, Hotter D, Bibollet-Ruche F, Plenderleith LJ, Peeters M, Geyer M, Sharp PM, Fackler OT, Hahn BH, Kirchhoff F. Kluge SF, et al. Among authors: learn gh. Cell Host Microbe. 2014 Nov 12;16(5):639-50. doi: 10.1016/j.chom.2014.10.002. Epub 2014 Nov 12. Cell Host Microbe. 2014. PMID: 25525794 Free PMC article.
Efficient Vpu-Mediated Tetherin Antagonism by an HIV-1 Group O Strain.
Mack K, Starz K, Sauter D, Langer S, Bibollet-Ruche F, Learn GH, Stürzel CM, Leoz M, Plantier JC, Geyer M, Hahn BH, Kirchhoff F. Mack K, et al. Among authors: learn gh. J Virol. 2017 Feb 28;91(6):e02177-16. doi: 10.1128/JVI.02177-16. Print 2017 Mar 15. J Virol. 2017. PMID: 28077643 Free PMC article.
Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein.
Sauter D, Unterweger D, Vogl M, Usmani SM, Heigele A, Kluge SF, Hermkes E, Moll M, Barker E, Peeters M, Learn GH, Bibollet-Ruche F, Fritz JV, Fackler OT, Hahn BH, Kirchhoff F. Sauter D, et al. Among authors: learn gh. PLoS Pathog. 2012 Dec;8(12):e1003093. doi: 10.1371/journal.ppat.1003093. Epub 2012 Dec 20. PLoS Pathog. 2012. PMID: 23308067 Free PMC article.
133 results