Le Hegarat L - Search Results

1

Preface to the Special Issue dedicated to the 47th annual conference of the European Environmental Mutagen and Genomics Society (EEMGS).

Stopper H, Knudsen LE, Le Hegarat L. Stopper H, et al. Among authors: le hegarat l. Mutat Res Genet Toxicol Environ Mutagen. 2020 Feb-Mar;850-851:503166. doi: 10.1016/j.mrgentox.2020.503166. Epub 2020 Mar 7. Mutat Res Genet Toxicol Environ Mutagen. 2020. PMID: 32247556 No abstract available.

2

Differential toxic effects of food contaminant mixtures in HepaRG cells after single or repeated treatments.

Kopp B, Le Hégarat L, Audebert M. Kopp B, et al. Among authors: le hegarat l. Mutat Res Genet Toxicol Environ Mutagen. 2020 Feb-Mar;850-851:503161. doi: 10.1016/j.mrgentox.2020.503161. Epub 2020 Feb 20. Mutat Res Genet Toxicol Environ Mutagen. 2020. PMID: 32247561

3

Benchmark dose analyses of γH2AX and pH3 endpoints for quantitative comparison of in vitro genotoxicity potential of lipophilic phycotoxins.

Le Hegarat L, Roudot AC, Fessard V. Le Hegarat L, et al. Mutat Res Genet Toxicol Environ Mutagen. 2020 Apr;852:503169. doi: 10.1016/j.mrgentox.2020.503169. Epub 2020 Mar 10. Mutat Res Genet Toxicol Environ Mutagen. 2020. PMID: 32265043

4

Hydrogen inhalation: in vivo rat genotoxicity tests.

Salomez-Ihl C, Tanguy S, Alcaraz JP, Davin C, Pascal-Moussellard V, Jabeur M, Bedouch P, Le Hegarat L, Fessard V, Blier AL, Huet S, Cinquin P, Boucher F. Salomez-Ihl C, et al. Among authors: le hegarat l. Mutat Res Genet Toxicol Environ Mutagen. 2024 Feb-Mar;894:503736. doi: 10.1016/j.mrgentox.2024.503736. Epub 2024 Feb 1. Mutat Res Genet Toxicol Environ Mutagen. 2024. PMID: 38432775

5

Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays.

Le Hegarat L, Dumont J, Josse R, Huet S, Lanceleur R, Mourot A, Poul JM, Guguen-Guillouzo C, Guillouzo A, Fessard V. Le Hegarat L, et al. Mutagenesis. 2010 Nov;25(6):555-60. doi: 10.1093/mutage/geq039. Epub 2010 Jul 30. Mutagenesis. 2010. PMID: 20675360

6

A co-culture system of human intestinal Caco-2 cells and lymphoblastoid TK6 cells for investigating the genotoxicity of oral compounds.

Le Hégarat L, Huet S, Fessard V. Le Hégarat L, et al. Mutagenesis. 2012 Nov;27(6):631-6. doi: 10.1093/mutage/ges028. Epub 2012 Jul 27. Mutagenesis. 2012. PMID: 22844081

7

The PERICLES research program: an integrated approach to characterize the combined effects of mixtures of pesticide residues to which the French population is exposed.

Crépet A, Héraud F, Béchaux C, Gouze ME, Pierlot S, Fastier A, Leblanc JCh, Le Hégarat L, Takakura N, Fessard V, Tressou J, Maximilien R, de Sousa G, Nawaz A, Zucchini-Pascal N, Rahmani R, Audebert M, Graillot V, Cravedi JP. Crépet A, et al. Among authors: le hegarat l. Toxicology. 2013 Nov 16;313(2-3):83-93. doi: 10.1016/j.tox.2013.04.005. Epub 2013 Apr 16. Toxicology. 2013. PMID: 23603198

8

Synergic toxic effects of food contaminant mixtures in human cells.

Kopp B, Sanders P, Alassane-Kpembi I, Fessard V, Zalko D, Le Hégarat L, Audebert M. Kopp B, et al. Among authors: le hegarat l. Mutagenesis. 2020 Aug 18:geaa019. doi: 10.1093/mutage/geaa019. Online ahead of print. Mutagenesis. 2020. PMID: 32809012

9

Towards better prediction of xenobiotic genotoxicity: CometChip technology coupled with a 3D model of HepaRG human liver cells.

Barranger A, Le Hégarat L. Barranger A, et al. Among authors: le hegarat l. Arch Toxicol. 2022 Jul;96(7):2087-2095. doi: 10.1007/s00204-022-03292-4. Epub 2022 Apr 13. Arch Toxicol. 2022. PMID: 35419617

10

In vivo genotoxic potential of microcystin-LR: a cyanobacterial toxin, investigated both by the unscheduled DNA synthesis (UDS) and the comet assays after intravenous administration.

Gaudin J, Le Hegarat L, Nesslany F, Marzin D, Fessard V. Gaudin J, et al. Among authors: le hegarat l. Environ Toxicol. 2009 Apr;24(2):200-9. doi: 10.1002/tox.20417. Environ Toxicol. 2009. PMID: 18561296

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