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Inactivation of the Nuclear Orphan Receptor COUP-TFII by Small Chemicals.
Le Guével R, Oger F, Martinez-Jimenez CP, Bizot M, Gheeraert C, Firmin F, Ploton M, Kretova M, Palierne G, Staels B, Barath P, Talianidis I, Lefebvre P, Eeckhoute J, Salbert G. Le Guével R, et al. ACS Chem Biol. 2017 Mar 17;12(3):654-663. doi: 10.1021/acschembio.6b00593. Epub 2017 Jan 13. ACS Chem Biol. 2017. PMID: 28059499
Biological and biophysical properties of the histone deacetylase inhibitor suberoylanilide hydroxamic acid are affected by the presence of short alkyl groups on the phenyl ring.
Oger F, Lecorgne A, Sala E, Nardese V, Demay F, Chevance S, Desravines DC, Aleksandrova N, Le Guével R, Lorenzi S, Beccari AR, Barath P, Hart DJ, Bondon A, Carettoni D, Simonneaux G, Salbert G. Oger F, et al. Among authors: le guevel r. J Med Chem. 2010 Mar 11;53(5):1937-50. doi: 10.1021/jm901561u. J Med Chem. 2010. PMID: 20143840
Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors.
Ouach A, Boulahjar R, Vala C, Bourg S, Bonnet P, Guguen-Guillouzo C, Ravache M, Le Guevel R, Lozach O, Lazar S, Troin Y, Meijer L, Ruchaud S, Akssira M, Guillaumet G, Routier S. Ouach A, et al. Among authors: le guevel r. Eur J Med Chem. 2016 Jun 10;115:311-25. doi: 10.1016/j.ejmech.2016.02.072. Epub 2016 Mar 2. Eur J Med Chem. 2016. PMID: 27019296
Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains.
Murthy AVR, Narendar V, Sampath Kumar N, Aparna P, Bhavani AKD, Solhi H, Le Guevel R, Roul J, Gautier F, Juin P, Reddy CR, Mosset P, Levoin N, Grée R. Murthy AVR, et al. Among authors: le guevel r. Bioorg Med Chem Lett. 2021 Nov 15;52:128390. doi: 10.1016/j.bmcl.2021.128390. Epub 2021 Sep 30. Bioorg Med Chem Lett. 2021. PMID: 34601029 Free article.
47 results