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Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells.
Wang YY, Attané C, Milhas D, Dirat B, Dauvillier S, Guerard A, Gilhodes J, Lazar I, Alet N, Laurent V, Le Gonidec S, Biard D, Hervé C, Bost F, Ren GS, Bono F, Escourrou G, Prentki M, Nieto L, Valet P, Muller C. Wang YY, et al. Among authors: le gonidec s. JCI Insight. 2017 Feb 23;2(4):e87489. doi: 10.1172/jci.insight.87489. JCI Insight. 2017. PMID: 28239646 Free PMC article.
Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP).
Lehuédé C, Li X, Dauvillier S, Vaysse C, Franchet C, Clement E, Esteve D, Longué M, Chaltiel L, Le Gonidec S, Lazar I, Geneste A, Dumontet C, Valet P, Nieto L, Fallone F, Muller C. Lehuédé C, et al. Among authors: le gonidec s. Breast Cancer Res. 2019 Jan 17;21(1):7. doi: 10.1186/s13058-018-1088-6. Breast Cancer Res. 2019. PMID: 30654824 Free PMC article.
Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity.
Laurent V, Guérard A, Mazerolles C, Le Gonidec S, Toulet A, Nieto L, Zaidi F, Majed B, Garandeau D, Socrier Y, Golzio M, Cadoudal T, Chaoui K, Dray C, Monsarrat B, Schiltz O, Wang YY, Couderc B, Valet P, Malavaud B, Muller C. Laurent V, et al. Among authors: le gonidec s. Nat Commun. 2016 Jan 12;7:10230. doi: 10.1038/ncomms10230. Nat Commun. 2016. PMID: 26756352 Free PMC article.
Periprostatic Adipose Tissue Favors Prostate Cancer Cell Invasion in an Obesity-Dependent Manner: Role of Oxidative Stress.
Laurent V, Toulet A, Attané C, Milhas D, Dauvillier S, Zaidi F, Clement E, Cinato M, Le Gonidec S, Guérard A, Lehuédé C, Garandeau D, Nieto L, Renaud-Gabardos E, Prats AC, Valet P, Malavaud B, Muller C. Laurent V, et al. Among authors: le gonidec s. Mol Cancer Res. 2019 Mar;17(3):821-835. doi: 10.1158/1541-7786.MCR-18-0748. Epub 2019 Jan 3. Mol Cancer Res. 2019. PMID: 30606769
Adipocyte extracellular vesicles carry enzymes and fatty acids that stimulate mitochondrial metabolism and remodeling in tumor cells.
Clement E, Lazar I, Attané C, Carrié L, Dauvillier S, Ducoux-Petit M, Esteve D, Menneteau T, Moutahir M, Le Gonidec S, Dalle S, Valet P, Burlet-Schiltz O, Muller C, Nieto L. Clement E, et al. Among authors: le gonidec s. EMBO J. 2020 Feb 3;39(3):e102525. doi: 10.15252/embj.2019102525. Epub 2020 Jan 10. EMBO J. 2020. PMID: 31919869 Free PMC article.
31 results