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Type 2 diabetes is associated with impaired jejunal enteroendocrine GLP-1 cell lineage in human obesity.
Osinski C, Le Gléau L, Poitou C, de Toro-Martin J, Genser L, Fradet M, Soula HA, Leturque A, Blugeon C, Jourdren L, Hubert EL, Clément K, Serradas P, Ribeiro A. Osinski C, et al. Among authors: le gleau l. Int J Obes (Lond). 2021 Jan;45(1):170-183. doi: 10.1038/s41366-020-00694-1. Epub 2020 Oct 9. Int J Obes (Lond). 2021. PMID: 33037328 Free PMC article. Clinical Trial.
Intestinal alteration of α-gustducin and sweet taste signaling pathway in metabolic diseases is partly rescued after weight loss and diabetes remission.
Le Gléau L, Rouault C, Osinski C, Prifti E, Soula HA, Debédat J, Busieau P, Amouyal C, Clément K, Andreelli F, Ribeiro A, Serradas P. Le Gléau L, et al. Am J Physiol Endocrinol Metab. 2021 Sep 1;321(3):E417-E432. doi: 10.1152/ajpendo.00071.2021. Epub 2021 Aug 2. Am J Physiol Endocrinol Metab. 2021. PMID: 34338041 Free article.