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Biomimetic synthesis of Tramadol.
Lecerf-Schmidt F, Haudecoeur R, Peres B, Ferreira Queiroz MM, Marcourt L, Challal S, Ferreira Queiroz E, Sotoing Taiwe G, Lomberget T, Le Borgne M, Wolfender JL, De Waard M, Robins RJ, Boumendjel A. Lecerf-Schmidt F, et al. Among authors: le borgne m. Chem Commun (Camb). 2015 Oct 4;51(77):14451-3. doi: 10.1039/c5cc05948h. Epub 2015 Aug 12. Chem Commun (Camb). 2015. PMID: 26267411
Occurrence of the synthetic analgesic tramadol in an African medicinal plant.
Boumendjel A, Sotoing Taïwe G, Ngo Bum E, Chabrol T, Beney C, Sinniger V, Haudecoeur R, Marcourt L, Challal S, Ferreira Queiroz E, Souard F, Le Borgne M, Lomberget T, Depaulis A, Lavaud C, Robins R, Wolfender JL, Bonaz B, De Waard M. Boumendjel A, et al. Among authors: le borgne m. Angew Chem Int Ed Engl. 2013 Nov 4;52(45):11780-4. doi: 10.1002/anie.201305697. Epub 2013 Sep 6. Angew Chem Int Ed Engl. 2013. PMID: 24014188 No abstract available.
2-Indolylmethylenebenzofuranones as first effective inhibitors of ABCC2.
Baiceanu E, Nguyen KA, Gonzalez-Lobato L, Nasr R, Baubichon-Cortay H, Loghin F, Le Borgne M, Chow L, Boumendjel A, Peuchmaur M, Falson P. Baiceanu E, et al. Among authors: le borgne m. Eur J Med Chem. 2016 Oct 21;122:408-418. doi: 10.1016/j.ejmech.2016.06.039. Epub 2016 Jun 27. Eur J Med Chem. 2016. PMID: 27393949
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action.
Bestgen B, Kufareva I, Seetoh W, Abell C, Hartmann RW, Abagyan R, Le Borgne M, Filhol O, Cochet C, Lomberget T, Engel M. Bestgen B, et al. Among authors: le borgne m. J Med Chem. 2019 Feb 28;62(4):1817-1836. doi: 10.1021/acs.jmedchem.8b01765. Epub 2019 Feb 13. J Med Chem. 2019. PMID: 30689946 Free PMC article.
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site.
Bestgen B, Krimm I, Kufareva I, Kamal AAM, Seetoh WG, Abell C, Hartmann RW, Abagyan R, Cochet C, Le Borgne M, Engel M, Lomberget T. Bestgen B, et al. Among authors: le borgne m. J Med Chem. 2019 Feb 28;62(4):1803-1816. doi: 10.1021/acs.jmedchem.8b01766. Epub 2019 Feb 18. J Med Chem. 2019. PMID: 30689953 Free PMC article.
Fragment Linking Strategies for Structure-Based Drug Design.
Bancet A, Raingeval C, Lomberget T, Le Borgne M, Guichou JF, Krimm I. Bancet A, et al. Among authors: le borgne m. J Med Chem. 2020 Oct 22;63(20):11420-11435. doi: 10.1021/acs.jmedchem.0c00242. Epub 2020 Jun 23. J Med Chem. 2020. PMID: 32539387 Review.
128 results