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Intratumoral delivery of TransCon™ TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction.
Cancer Cell Int. 2022 Sep 19;22(1):286. doi: 10.1186/s12935-022-02708-6.
Cancer Cell Int. 2022.
PMID: 36123697
Free PMC article.
Degradable Hydrogel for Sustained Localized Delivery of Anti-Tumor Drugs.
Lessmann T, Jones SA, Voigt T, Weisbrod S, Kracker O, Winter S, Zúñiga LA, Stark S, Bisek N, Sprogøe K.
Lessmann T, et al.
J Pharm Sci. 2023 Nov;112(11):2843-2852. doi: 10.1016/j.xphs.2023.05.018. Epub 2023 Jun 4.
J Pharm Sci. 2023.
PMID: 37279836
Free article.
Item in Clipboard
Identification of a 60S preribosomal particle that is closely linked to nuclear export.
Bassler J, Grandi P, Gadal O, Lessmann T, Petfalski E, Tollervey D, Lechner J, Hurt E.
Bassler J, et al. Among authors: lessmann t.
Mol Cell. 2001 Sep;8(3):517-29. doi: 10.1016/s1097-2765(01)00342-2.
Mol Cell. 2001.
PMID: 11583615
Free article.
Item in Clipboard
Chemical biology--identification of small molecule modulators of cellular activity by natural product inspired synthesis.
Hübel K, Lessmann T, Waldmann H.
Hübel K, et al. Among authors: lessmann t.
Chem Soc Rev. 2008 Jul;37(7):1361-74. doi: 10.1039/b704729k. Epub 2008 May 14.
Chem Soc Rev. 2008.
PMID: 18568162
Review.
Item in Clipboard
Natural product-derived modulators of cell cycle progression and viral entry by enantioselective oxa Diels-Alder reactions on the solid phase.
Lessmann T, Leuenberger MG, Menninger S, Lopez-Canet M, Müller O, Hümmer S, Bormann J, Korn K, Fava E, Zerial M, Mayer TU, Waldmann H.
Lessmann T, et al.
Chem Biol. 2007 Apr;14(4):443-51. doi: 10.1016/j.chembiol.2007.02.008.
Chem Biol. 2007.
PMID: 17462579
Item in Clipboard
Biology-oriented synthesis of stereochemically diverse natural-product-derived compound collections by iterative allylations on a solid support.
Umarye JD, Lessmann T, García AB, Mamane V, Sommer S, Waldmann H.
Umarye JD, et al. Among authors: lessmann t.
Chemistry. 2007;13(12):3305-19. doi: 10.1002/chem.200601698.
Chemistry. 2007.
PMID: 17310497
Item in Clipboard
Stereocomplementary synthesis of a natural product-derived compound collection on a solid phase.
Garcia AB, Lessmann T, Umarye JD, Mamane V, Sommer S, Waldmann H.
Garcia AB, et al. Among authors: lessmann t.
Chem Commun (Camb). 2006 Oct 1;(37):3868-70. doi: 10.1039/b607816h. Epub 2006 Jul 31.
Chem Commun (Camb). 2006.
PMID: 17268653
Item in Clipboard
Enantioselective synthesis on the solid phase.
Lessmann T, Waldmann H.
Lessmann T, et al.
Chem Commun (Camb). 2006 Aug 28;(32):3380-9. doi: 10.1039/b602822e. Epub 2006 May 3.
Chem Commun (Camb). 2006.
PMID: 16896470
Review.
Item in Clipboard
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