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Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation.
Jiang Q, Isquith J, Zipeto MA, Diep RH, Pham J, Delos Santos N, Reynoso E, Chau J, Leu H, Lazzari E, Melese E, Ma W, Fang R, Minden M, Morris S, Ren B, Pineda G, Holm F, Jamieson C. Jiang Q, et al. Among authors: lazzari e. Cancer Cell. 2019 Jan 14;35(1):81-94.e7. doi: 10.1016/j.ccell.2018.11.017. Epub 2019 Jan 3. Cancer Cell. 2019. PMID: 30612940 Free PMC article.
An RNA editing fingerprint of cancer stem cell reprogramming.
Crews LA, Jiang Q, Zipeto MA, Lazzari E, Court AC, Ali S, Barrett CL, Frazer KA, Jamieson CH. Crews LA, et al. Among authors: lazzari e. J Transl Med. 2015 Feb 12;13:52. doi: 10.1186/s12967-014-0370-3. J Transl Med. 2015. PMID: 25889244 Free PMC article.
RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML.
Crews LA, Balaian L, Delos Santos NP, Leu HS, Court AC, Lazzari E, Sadarangani A, Zipeto MA, La Clair JJ, Villa R, Kulidjian A, Storb R, Morris SR, Ball ED, Burkart MD, Jamieson CHM. Crews LA, et al. Among authors: lazzari e. Cell Stem Cell. 2016 Nov 3;19(5):599-612. doi: 10.1016/j.stem.2016.08.003. Epub 2016 Aug 25. Cell Stem Cell. 2016. PMID: 27570067 Free PMC article.
Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche.
Colombo M, Galletti S, Bulfamante G, Falleni M, Tosi D, Todoerti K, Lazzari E, Crews LA, Jamieson CH, Ravaioli S, Baccianti F, Garavelli S, Platonova N, Neri A, Chiaramonte R. Colombo M, et al. Among authors: lazzari e. Oncotarget. 2016 Aug 30;7(35):56013-56029. doi: 10.18632/oncotarget.10820. Oncotarget. 2016. PMID: 27463014 Free PMC article.
Notch signaling drives multiple myeloma induced osteoclastogenesis.
Colombo M, Thümmler K, Mirandola L, Garavelli S, Todoerti K, Apicella L, Lazzari E, Lancellotti M, Platonova N, Akbar M, Chiriva-Internati M, Soutar R, Neri A, Goodyear CS, Chiaramonte R. Colombo M, et al. Among authors: lazzari e. Oncotarget. 2014 Nov 15;5(21):10393-406. doi: 10.18632/oncotarget.2084. Oncotarget. 2014. PMID: 25257302 Free PMC article.
Multiple myeloma exploits Jagged1 and Jagged2 to promote intrinsic and bone marrow-dependent drug resistance.
Colombo M, Garavelli S, Mazzola M, Platonova N, Giannandrea D, Colella R, Apicella L, Lancellotti M, Lesma E, Ancona S, Palano MT, Barbieri M, Taiana E, Lazzari E, Basile A, Turrini M, Pistocchi A, Neri A, Chiaramonte R. Colombo M, et al. Among authors: lazzari e. Haematologica. 2020 Jul;105(7):1925-1936. doi: 10.3324/haematol.2019.221077. Epub 2019 Oct 3. Haematologica. 2020. PMID: 31582544 Free PMC article.
250 results