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Identification of small molecules affecting the interaction between human hemoglobin and Staphylococcus aureus IsdB hemophore.
Cozzi M, Failla M, Gianquinto E, Kovachka S, Buoli Comani V, Compari C, De Bei O, Giaccari R, Marchesani F, Marchetti M, Ronda L, Rolando B, Baroni M, Cruciani G, Campanini B, Bettati S, Faggiano S, Lazzarato L, Spyrakis F. Cozzi M, et al. Among authors: lazzarato l. Sci Rep. 2024 Apr 9;14(1):8272. doi: 10.1038/s41598-024-55931-8. Sci Rep. 2024. PMID: 38594253 Free PMC article.
Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.
De Bei O, Marchetti M, Ronda L, Gianquinto E, Lazzarato L, Chirgadze DY, Hardwick SW, Cooper LR, Spyrakis F, Luisi BF, Campanini B, Bettati S. De Bei O, et al. Among authors: lazzarato l. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2116708119. doi: 10.1073/pnas.2116708119. Epub 2022 Mar 31. Proc Natl Acad Sci U S A. 2022. PMID: 35357971 Free PMC article.
Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-β-Lactamases and Synergistic Activity on Resistant Bacteria.
Bersani M, Failla M, Vascon F, Gianquinto E, Bertarini L, Baroni M, Cruciani G, Verdirosa F, Sannio F, Docquier JD, Cendron L, Spyrakis F, Lazzarato L, Tondi D. Bersani M, et al. Among authors: lazzarato l. Pharmaceuticals (Basel). 2023 Dec 2;16(12):1682. doi: 10.3390/ph16121682. Pharmaceuticals (Basel). 2023. PMID: 38139809 Free PMC article.
Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae.
Parisi C, Failla M, Fraix A, Rolando B, Gianquinto E, Spyrakis F, Gazzano E, Riganti C, Lazzarato L, Fruttero R, Gasco A, Sortino S. Parisi C, et al. Among authors: lazzarato l. Chemistry. 2019 Aug 22;25(47):11080-11084. doi: 10.1002/chem.201902062. Epub 2019 Jul 4. Chemistry. 2019. PMID: 31074543
A generator of peroxynitrite activatable with red light.
Parisi C, Failla M, Fraix A, Menilli L, Moret F, Reddi E, Rolando B, Spyrakis F, Lazzarato L, Fruttero R, Gasco A, Sortino S. Parisi C, et al. Among authors: lazzarato l. Chem Sci. 2021 Mar 4;12(13):4740-4746. doi: 10.1039/d0sc06970a. Chem Sci. 2021. PMID: 34163730 Free PMC article.
Tuning the Hydrophobicity of a Mitochondria-Targeted NO Photodonor.
Sodano F, Rolando B, Spyrakis F, Failla M, Lazzarato L, Gazzano E, Riganti C, Fruttero R, Gasco A, Sortino S. Sodano F, et al. Among authors: lazzarato l. ChemMedChem. 2018 Jun 20;13(12):1238-1245. doi: 10.1002/cmdc.201800088. Epub 2018 May 8. ChemMedChem. 2018. PMID: 29633541
87 results