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Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders.
Nabais MF, Laws SM, Lin T, Vallerga CL, Armstrong NJ, Blair IP, Kwok JB, Mather KA, Mellick GD, Sachdev PS, Wallace L, Henders AK, Zwamborn RAJ, Hop PJ, Lunnon K, Pishva E, Roubroeks JAY, Soininen H, Tsolaki M, Mecocci P, Lovestone S, Kłoszewska I, Vellas B; Australian Imaging Biomarkers and Lifestyle study; Alzheimer’s Disease Neuroimaging Initiative; Furlong S, Garton FC, Henderson RD, Mathers S, McCombe PA, Needham M, Ngo ST, Nicholson G, Pamphlett R, Rowe DB, Steyn FJ, Williams KL, Anderson TJ, Bentley SR, Dalrymple-Alford J, Fowder J, Gratten J, Halliday G, Hickie IB, Kennedy M, Lewis SJG, Montgomery GW, Pearson J, Pitcher TL, Silburn P, Zhang F, Visscher PM, Yang J, Stevenson AJ, Hillary RF, Marioni RE, Harris SE, Deary IJ, Jones AR, Shatunov A, Iacoangeli A, van Rheenen W, van den Berg LH, Shaw PJ, Shaw CE, Morrison KE, Al-Chalabi A, Veldink JH, Hannon E, Mill J, Wray NR, McRae AF. Nabais MF, et al. Among authors: laws sm. Genome Biol. 2021 Mar 26;22(1):90. doi: 10.1186/s13059-021-02275-5. Genome Biol. 2021. PMID: 33771206 Free PMC article.
Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture.
Zhang Q, Sidorenko J, Couvy-Duchesne B, Marioni RE, Wright MJ, Goate AM, Marcora E, Huang KL, Porter T, Laws SM; Australian Imaging Biomarkers and Lifestyle (AIBL) Study; Sachdev PS, Mather KA, Armstrong NJ, Thalamuthu A, Brodaty H, Yengo L, Yang J, Wray NR, McRae AF, Visscher PM. Zhang Q, et al. Among authors: laws sm. Nat Commun. 2020 Sep 23;11(1):4799. doi: 10.1038/s41467-020-18534-1. Nat Commun. 2020. PMID: 32968074 Free PMC article.
Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease.
Cadby G, Giles C, Melton PE, Huynh K, Mellett NA, Duong T, Nguyen A, Cinel M, Smith A, Olshansky G, Wang T, Brozynska M, Inouye M, McCarthy NS, Ariff A, Hung J, Hui J, Beilby J, Dubé MP, Watts GF, Shah S, Wray NR, Lim WLF, Chatterjee P, Martins I, Laws SM, Porter T, Vacher M, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Taddei K, Arnold M, Kastenmüller G, Nho K, Saykin AJ, Han X, Kaddurah-Daouk R, Martins RN, Blangero J, Meikle PJ, Moses EK. Cadby G, et al. Among authors: laws sm. Nat Commun. 2022 Jun 6;13(1):3124. doi: 10.1038/s41467-022-30875-7. Nat Commun. 2022. PMID: 35668104 Free PMC article.
Polygenic resilience scores capture protective genetic effects for Alzheimer's disease.
Hou J, Hess JL, Armstrong N, Bis JC, Grenier-Boley B, Karlsson IK, Leonenko G, Numbers K, O'Brien EK, Shadrin A, Thalamuthu A, Yang Q, Andreassen OA, Brodaty H, Gatz M, Kochan NA, Lambert JC, Laws SM, Masters CL, Mather KA, Pedersen NL, Posthuma D, Sachdev PS, Williams J; Alzheimer’s Disease Neuroimaging Initiative; Fan CC, Faraone SV, Fennema-Notestine C, Lin SJ, Escott-Price V, Holmans P, Seshadri S, Tsuang MT, Kremen WS, Glatt SJ. Hou J, et al. Among authors: laws sm. Transl Psychiatry. 2022 Jul 25;12(1):296. doi: 10.1038/s41398-022-02055-0. Transl Psychiatry. 2022. PMID: 35879306 Free PMC article.
Sixteen-Year Longitudinal Evaluation of Blood-Based DNA Methylation Biomarkers for Early Prediction of Alzheimer's Disease.
Schäfer Hackenhaar F, Josefsson M, Nordin Adolfsson A, Landfors M, Kauppi K, Porter T, Milicic L, Laws SM, Hultdin M, Adolfsson R, Degerman S, Pudas S; Australian Imaging Biomarkers and Lifestyle Study. Schäfer Hackenhaar F, et al. Among authors: laws sm. J Alzheimers Dis. 2023;94(4):1443-1464. doi: 10.3233/JAD-230039. J Alzheimers Dis. 2023. PMID: 37393498 Free PMC article. Review.
Impact of APOE-ε4 carriage on the onset and rates of neocortical Aβ-amyloid deposition.
Burnham SC, Laws SM, Budgeon CA, Doré V, Porter T, Bourgeat P, Buckley RF, Murray K, Ellis KA, Turlach BA, Salvado O, Ames D, Martins RN, Rentz D, Masters CL, Rowe CC, Villemagne VL; Alzheimer's Disease Neuroimaging Initiative; AIBL Research Group. Burnham SC, et al. Among authors: laws sm. Neurobiol Aging. 2020 Nov;95:46-55. doi: 10.1016/j.neurobiolaging.2020.06.001. Epub 2020 Jun 10. Neurobiol Aging. 2020. PMID: 32750666 Free PMC article.
KL∗VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗4 carriers.
Belloy ME, Eger SJ, Le Guen Y, Napolioni V, Deters KD, Yang HS, Scelsi MA, Porter T, James SN, Wong A, Schott JM, Sperling RA, Laws SM, Mormino EC, He Z, Han SS, Altmann A, Greicius MD; A4 Study Team; Insight 46 Study Team; Australian Imaging Biomarkers and Lifestyle (AIBL) Study; Alzheimer's Disease Neuroimaging Initiative. Belloy ME, et al. Among authors: laws sm. Neurobiol Aging. 2021 May;101:123-129. doi: 10.1016/j.neurobiolaging.2021.01.008. Epub 2021 Jan 23. Neurobiol Aging. 2021. PMID: 33610961 Free PMC article.
Alzheimer's disease research progress in Australia: The Alzheimer's Association International Conference Satellite Symposium in Sydney.
Sexton CE, Anstey KJ, Baldacci F, Barnum CJ, Barron AM, Blennow K, Brodaty H, Burnham S, Elahi FM, Götz J, Jeon YH, Koronyo-Hamaoui M, Landau SM, Lautenschlager NT, Laws SM, Lipnicki DM, Lu H, Masters CL, Moyle W, Nakamura A, Pasinetti GM, Rao N, Rowe C, Sachdev PS, Schofield PR, Sigurdsson EM, Smith K, Srikanth V, Szoeke C, Tansey MG, Whitmer R, Wilcock D, Wong TY, Bain LJ, Carrillo MC. Sexton CE, et al. Among authors: laws sm. Alzheimers Dement. 2022 Jan;18(1):178-190. doi: 10.1002/alz.12380. Epub 2021 May 31. Alzheimers Dement. 2022. PMID: 34058063 Free PMC article. Review.
176 results