Lavecchia A - Search Results

1

Selective PPARγ modulators for Type 2 diabetes treatment: how far have we come and what does the future hold?

Lavecchia A, Cerchia C. Lavecchia A, et al. Future Med Chem. 2018 Apr 1;10(7):703-705. doi: 10.4155/fmc-2018-0021. Epub 2018 Apr 19. Future Med Chem. 2018. PMID: 29671628 No abstract available.

2

Modeling of kappa-opioid receptor/agonists interactions using pharmacophore-based and docking simulations.

Lavecchia A, Greco G, Novellino E, Vittorio F, Ronsisvalle G. Lavecchia A, et al. J Med Chem. 2000 Jun 1;43(11):2124-34. doi: 10.1021/jm991161k. J Med Chem. 2000. PMID: 10841791

3

Antitumor agents. 1. Synthesis, biological evaluation, and molecular modeling of 5H-pyrido[3,2-a]phenoxazin-5-one, a compound with potent antiproliferative activity.

Bolognese A, Correale G, Manfra M, Lavecchia A, Mazzoni O, Novellino E, Barone V, Pani A, Tramontano E, La Colla P, Murgioni C, Serra I, Setzu G, Loddo R. Bolognese A, et al. Among authors: lavecchia a. J Med Chem. 2002 Nov 21;45(24):5205-16. doi: 10.1021/jm020913z. J Med Chem. 2002. PMID: 12431048

4

Antitumor agents. 3. Design, synthesis, and biological evaluation of new pyridoisoquinolindione and dihydrothienoquinolindione derivatives with potent cytotoxic activity.

Bolognese A, Correale G, Manfra M, Lavecchia A, Mazzoni O, Novellino E, La Colla P, Sanna G, Loddo R. Bolognese A, et al. Among authors: lavecchia a. J Med Chem. 2004 Feb 12;47(4):849-58. doi: 10.1021/jm030918b. J Med Chem. 2004. PMID: 14761187

5

Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists.

Lavecchia A, Cosconati S, Novellino E. Lavecchia A, et al. J Med Chem. 2005 Apr 7;48(7):2480-92. doi: 10.1021/jm049110x. J Med Chem. 2005. PMID: 15801838

6

Synthesis, pharmacological evaluation, and molecular modeling studies of novel peptidic CAAX analogues as farnesyl-protein-transferase inhibitors.

Santagada V, Caliendo G, Severino B, Lavecchia A, Perissutti E, Fiorino F, Zampella A, Sepe V, Califano D, Santelli G, Novellino E. Santagada V, et al. Among authors: lavecchia a. J Med Chem. 2006 Mar 23;49(6):1882-90. doi: 10.1021/jm0506165. J Med Chem. 2006. PMID: 16539374

7

Antitumor agents. 5. synthesis, structure-activity relationships, and biological evaluation of dimethyl-5H-pyridophenoxazin-5-ones, tetrahydro-5h-benzopyridophenoxazin-5-ones, and 5h-benzopyridophenoxazin-5-ones with potent antiproliferative activity.

Bolognese A, Correale G, Manfra M, Lavecchia A, Novellino E, Pepe S. Bolognese A, et al. Among authors: lavecchia a. J Med Chem. 2006 Aug 24;49(17):5110-8. doi: 10.1021/jm050745l. J Med Chem. 2006. PMID: 16913700

8

Characterizing the 1,4-dihydropyridines binding interactions in the L-type Ca2+ channel: model construction and docking calculations.

Cosconati S, Marinelli L, Lavecchia A, Novellino E. Cosconati S, et al. Among authors: lavecchia a. J Med Chem. 2007 Apr 5;50(7):1504-13. doi: 10.1021/jm061245a. Epub 2007 Mar 3. J Med Chem. 2007. PMID: 17335186

9

Antitumor agents 6. Synthesis, structure-activity relationships, and biological evaluation of spiro[imidazolidine-4,3'-thieno[2,3-g]quinoline]-tetraones and spiro[thieno[2,3-g]quinoline-3,5'-[1,2,4]triazinane]-tetraones with potent antiproliferative activity.

Bolognese A, Correale G, Manfra M, Esposito A, Novellino E, Lavecchia A. Bolognese A, et al. Among authors: lavecchia a. J Med Chem. 2008 Dec 25;51(24):8148-57. doi: 10.1021/jm8007689. J Med Chem. 2008. PMID: 19053767

10

Discovery of new inhibitors of Cdc25B dual specificity phosphatases by structure-based virtual screening.

Lavecchia A, Di Giovanni C, Pesapane A, Montuori N, Ragno P, Martucci NM, Masullo M, De Vendittis E, Novellino E. Lavecchia A, et al. J Med Chem. 2012 May 10;55(9):4142-58. doi: 10.1021/jm201624h. Epub 2012 May 1. J Med Chem. 2012. PMID: 22524450

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