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Loss of α-actinin-3 during human evolution provides superior cold resilience and muscle heat generation.
Wyckelsma VL, Venckunas T, Houweling PJ, Schlittler M, Lauschke VM, Tiong CF, Wood HD, Ivarsson N, Paulauskas H, Eimantas N, Andersson DC, North KN, Brazaitis M, Westerblad H. Wyckelsma VL, et al. Among authors: lauschke vm. Am J Hum Genet. 2021 Mar 4;108(3):446-457. doi: 10.1016/j.ajhg.2021.01.013. Epub 2021 Feb 17. Am J Hum Genet. 2021. PMID: 33600773 Free PMC article.
Genetic testing is superior over endogenous pharmacometabolomic markers to predict safety of haloperidol in patients with alcohol-induced psychotic disorder.
Skryabin V, Zastrozhin M, Parkhomenko A, Lauschke VM, Smirnov V, Petukhov A, Pankratenko E, Pozdnyakov S, Koporov S, Denisenko N, Akmalova K, Bryun E, Sychev D. Skryabin V, et al. Among authors: lauschke vm. Curr Drug Metab. 2022 Dec 28. doi: 10.2174/1389200224666221228112643. Online ahead of print. Curr Drug Metab. 2022. PMID: 36579390
Two different isoforms of osteopontin modulate myelination and axonal integrity.
Nilsson G, Mottahedin A, Zelco A, Lauschke VM, Ek CJ, Song J, Ardalan M, Hua S, Zhang X, Mallard C, Hagberg H, Leavenworth JW, Wang X. Nilsson G, et al. Among authors: lauschke vm. FASEB Bioadv. 2023 Jun 17;5(8):336-353. doi: 10.1096/fba.2023-00030. eCollection 2023 Aug. FASEB Bioadv. 2023. PMID: 37554545 Free PMC article.
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study.
Swen JJ, van der Wouden CH, Manson LE, Abdullah-Koolmees H, Blagec K, Blagus T, Böhringer S, Cambon-Thomsen A, Cecchin E, Cheung KC, Deneer VH, Dupui M, Ingelman-Sundberg M, Jonsson S, Joefield-Roka C, Just KS, Karlsson MO, Konta L, Koopmann R, Kriek M, Lehr T, Mitropoulou C, Rial-Sebbag E, Rollinson V, Roncato R, Samwald M, Schaeffeler E, Skokou M, Schwab M, Steinberger D, Stingl JC, Tremmel R, Turner RM, van Rhenen MH, Dávila Fajardo CL, Dolžan V, Patrinos GP, Pirmohamed M, Sunder-Plassmann G, Toffoli G, Guchelaar HJ; Ubiquitous Pharmacogenomics Consortium. Swen JJ, et al. Lancet. 2023 Feb 4;401(10374):347-356. doi: 10.1016/S0140-6736(22)01841-4. Lancet. 2023. PMID: 36739136 Clinical Trial.
Response to Mörseburg et al.
Wyckelsma VL, Venckunas T, Houweling PJ, Schlittler M, Lauschke VM, Tiong CF, Wood HD, Paulauskas H, Eimantas N, Andersson DC, North KN, Brazaitis M, Westerblad H. Wyckelsma VL, et al. Among authors: lauschke vm. Am J Hum Genet. 2022 May 5;109(5):973. doi: 10.1016/j.ajhg.2022.03.017. Am J Hum Genet. 2022. PMID: 35523148 Free PMC article. No abstract available.
Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control.
Gineste C, Youhanna S, Vorrink SU, Henriksson S, Hernández A, Cheng AJ, Chaillou T, Buttgereit A, Schneidereit D, Friedrich O, Hultenby K, Bruton JD, Ivarsson N, Sandblad L, Lauschke VM, Westerblad H. Gineste C, et al. Among authors: lauschke vm. iScience. 2022 Nov 22;25(12):105654. doi: 10.1016/j.isci.2022.105654. eCollection 2022 Dec 22. iScience. 2022. PMID: 36479146 Free PMC article.
171 results