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Maximizing the potential of aggressive mouse tumor models in preclinical drug testing.
Elghetany MT, Ho JM, Shi-Qi LH, Karthik S, Su JMF, Lin Q, Du Y, Shen J, Chow WY, Lau CC, Adesina A, Major A, Erdreich-Epstein A, Hui KM, Li XN, Teo WY. Elghetany MT, et al. Among authors: lau cc. Sci Rep. 2021 Jun 2;11(1):11580. doi: 10.1038/s41598-021-91167-6. Sci Rep. 2021. PMID: 34079014 Free PMC article.
Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors.
Qi L, Kogiso M, Du Y, Zhang H, Braun FK, Huang Y, Teo WY, Lindsay H, Zhao S, Baxter P, Zhao X, Yu L, Liu Z, Zhang X, Su JM, Adesina A, Yang J, Chintagumpala M, Perlaky L, Tsz-Kwong Man C, Lau CC, Li XN. Qi L, et al. Among authors: lau cc. Cancer Lett. 2020 Nov 28;493:197-206. doi: 10.1016/j.canlet.2020.08.035. Epub 2020 Sep 3. Cancer Lett. 2020. PMID: 32891713 Free PMC article.
Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of medulloblastoma and glioma.
Shu Q, Wong KK, Su JM, Adesina AM, Yu LT, Tsang YT, Antalffy BC, Baxter P, Perlaky L, Yang J, Dauser RC, Chintagumpala M, Blaney SM, Lau CC, Li XN. Shu Q, et al. Among authors: lau cc. Stem Cells. 2008 Jun;26(6):1414-24. doi: 10.1634/stemcells.2007-1009. Epub 2008 Apr 10. Stem Cells. 2008. PMID: 18403755
A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo.
Yu L, Baxter PA, Voicu H, Gurusiddappa S, Zhao Y, Adesina A, Man TK, Shu Q, Zhang YJ, Zhao XM, Su JM, Perlaky L, Dauser R, Chintagumpala M, Lau CC, Blaney SM, Rao PH, Leung HC, Li XN. Yu L, et al. Among authors: lau cc. Neuro Oncol. 2010 Jun;12(6):580-94. doi: 10.1093/neuonc/nop056. Epub 2010 Feb 8. Neuro Oncol. 2010. PMID: 20511191 Free PMC article.
Implications of tumor location on subtypes of medulloblastoma.
Teo WY, Shen J, Su JM, Yu A, Wang J, Chow WY, Li X, Jones J, Dauser R, Whitehead W, Adesina AM, Chintagumpala M, Man TK, Lau CC. Teo WY, et al. Among authors: lau cc. Pediatr Blood Cancer. 2013 Sep;60(9):1408-10. doi: 10.1002/pbc.24511. Epub 2013 Mar 19. Pediatr Blood Cancer. 2013. PMID: 23512859 Clinical Trial.
325 results