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Biased and g protein-independent signaling of chemokine receptors.
Steen A, Larsen O, Thiele S, Rosenkilde MM. Steen A, et al. Among authors: larsen o. Front Immunol. 2014 Jun 23;5:277. doi: 10.3389/fimmu.2014.00277. eCollection 2014. Front Immunol. 2014. PMID: 25002861 Free PMC article. Review.
Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo.
Spiess K, Jeppesen MG, Malmgaard-Clausen M, Krzywkowski K, Dulal K, Cheng T, Hjortø GM, Larsen O, Burg JS, Jarvis MA, Garcia KC, Zhu H, Kledal TN, Rosenkilde MM. Spiess K, et al. Among authors: larsen o. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8427-32. doi: 10.1073/pnas.1509392112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080445 Free PMC article.
Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding.
Barington L, Rummel PC, Lückmann M, Pihl H, Larsen O, Daugvilaite V, Johnsen AH, Frimurer TM, Karlshøj S, Rosenkilde MM. Barington L, et al. Among authors: larsen o. J Biol Chem. 2016 Jul 29;291(31):16208-20. doi: 10.1074/jbc.M115.706747. Epub 2016 May 19. J Biol Chem. 2016. PMID: 27226537 Free PMC article.
Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo.
Janssens R, Mortier A, Boff D, Vanheule V, Gouwy M, Franck C, Larsen O, Rosenkilde MM, Van Damme J, Amaral FA, Teixeira MM, Struyf S, Proost P. Janssens R, et al. Among authors: larsen o. Oncotarget. 2016 Sep 20;7(38):62439-62459. doi: 10.18632/oncotarget.11516. Oncotarget. 2016. PMID: 27566567 Free PMC article.
371 results