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Cytotoxic bis-3,4-dihydro-beta-carbolines and bis-beta-carbolines.
Jiang WQ, Charlet-Fagnère C, Sapi J, Laronze JY, Renard P, Pfeiffer B, Léonce S. Jiang WQ, et al. Among authors: laronze jy. J Enzyme Inhib Med Chem. 2002 Dec;17(6):369-74. doi: 10.1080/147563021000005631. J Enzyme Inhib Med Chem. 2002. PMID: 12683671
Introduction of the 4-(4-bromophenyl)benzenesulfonyl group to hydrazide analogs of Ilomastat leads to potent gelatinase B (MMP-9) inhibitors with improved selectivity.
Ledour G, Moroy G, Rouffet M, Bourguet E, Guillaume D, Decarme M, Elmourabit H, Augé F, Alix AJ, Laronze JY, Bellon G, Hornebeck W, Sapi J. Ledour G, et al. Among authors: laronze jy. Bioorg Med Chem. 2008 Sep 15;16(18):8745-59. doi: 10.1016/j.bmc.2008.07.041. Epub 2008 Jul 20. Bioorg Med Chem. 2008. PMID: 18782669
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