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Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification.
Zeng PYF, Cecchini MJ, Barrett JW, Shammas-Toma M, De Cecco L, Serafini MS, Cavalieri S, Licitra L, Hoebers F, Brakenhoff RH, Leemans CR, Scheckenbach K, Poli T, Wang X, Liu X, Laxague F, Prisman E, Poh C, Bose P, Dort JC, Shaikh MH, Ryan SEB, Dawson A, Khan MI, Howlett CJ, Stecho W, Plantinga P, Daniela da Silva S, Hier M, Khan H, MacNeil D, Mendez A, Yoo J, Fung K, Lang P, Winquist E, Palma DA, Ziai H, Amelio AL, Li SS, Boutros PC, Mymryk JS, Nichols AC. Zeng PYF, et al. Among authors: lang p. EBioMedicine. 2022 Dec;86:104373. doi: 10.1016/j.ebiom.2022.104373. Epub 2022 Nov 25. EBioMedicine. 2022. PMID: 36442320 Free PMC article.
Treatment de-escalation for HPV-associated oropharyngeal squamous cell carcinoma with radiotherapy vs. trans-oral surgery (ORATOR2): study protocol for a randomized phase II trial.
Nichols AC, Lang P, Prisman E, Berthelet E, Tran E, Hamilton S, Wu J, Fung K, de Almeida JR, Bayley A, Goldstein DP, Eskander A, Husain Z, Bahig H, Christopoulous A, Hier M, Sultanem K, Richardson K, Mlynarek A, Krishnan S, Le H, Yoo J, MacNeil SD, Mendez A, Winquist E, Read N, Venkatesan V, Kuruvilla S, Warner A, Mitchell S, Corsten M, Rajaraman M, Johnson-Obaseki S, Eapen L, Odell M, Chandarana S, Banerjee R, Dort J, Matthews TW, Hart R, Kerr P, Dowthwaite S, Gupta M, Zhang H, Wright J, Parker C, Wehrli B, Kwan K, Theurer J, Palma DA. Nichols AC, et al. Among authors: lang p. BMC Cancer. 2020 Feb 14;20(1):125. doi: 10.1186/s12885-020-6607-z. BMC Cancer. 2020. PMID: 32059705 Free PMC article. Clinical Trial.
Preservation of swallowing in resected oral cavity squamous cell carcinoma: examining radiation volume effects (PRESERVE): study protocol for a randomized phase II trial.
Lang P, Contreras J, Kalman N, Paterson C, Bahig H, Billfalk-Kelly A, Brennan S, Rock K, Read N, Venkatesan V, Sathya J, Mendez LC, MacNeil SD, Nichols AC, Fung K, Mendez A, Winquist E, Kuruvilla S, Stewart P, Warner A, Mitchell S, Theurer JA, Palma DA. Lang P, et al. Radiat Oncol. 2020 Aug 14;15(1):196. doi: 10.1186/s13014-020-01636-x. Radiat Oncol. 2020. PMID: 32795322 Free PMC article.
Modern treatment outcomes for early T-stage oropharyngeal cancer treated with intensity-modulated radiation therapy at a tertiary care institution.
Di Gravio EJ, Lang P, Kim HAJ, Chinnery T, Mundi N, MacNeil SD, Mendez A, Yoo J, Fung K, Mymryk JS, Barrett JW, Read N, Venkatesan V, Kuruvilla S, Mendez LC, Winquist E, Mitchell S, Mattonen SA, Nichols AC, Palma DA. Di Gravio EJ, et al. Among authors: lang p. Radiat Oncol. 2020 Nov 10;15(1):261. doi: 10.1186/s13014-020-01705-1. Radiat Oncol. 2020. PMID: 33168055 Free PMC article.
Analysis of the TCGA Dataset Reveals that Subsites of Laryngeal Squamous Cell Carcinoma are Molecularly Distinct.
Sorgini A, Kim HAJ, Zeng PYF, Shaikh MH, Mundi N, Ghasemi F, Di Gravio E, Khan H, MacNeil D, Khan MI, Mendez A, Yoo J, Fung K, Lang P, Palma DA, Mymryk JS, Barrett JW, Patel KB, Boutros PC, Nichols AC. Sorgini A, et al. Among authors: lang p. Cancers (Basel). 2020 Dec 31;13(1):105. doi: 10.3390/cancers13010105. Cancers (Basel). 2020. PMID: 33396315 Free PMC article.
All HPV-negative head and neck cancers are not the same: Analysis of the TCGA dataset reveals that anatomical sites have distinct mutation, transcriptome, hypoxia, and tumor microenvironment profiles.
Kim HAJ, Zeng PYF, Shaikh MH, Mundi N, Ghasemi F, Di Gravio E, Khan H, MacNeil D, Khan MI, Patel K, Mendez A, Yoo J, Fung K, Lang P, Palma DA, Mymryk JS, Barrett JW, Boutros PC, Nichols AC. Kim HAJ, et al. Among authors: lang p. Oral Oncol. 2021 May;116:105260. doi: 10.1016/j.oraloncology.2021.105260. Epub 2021 Mar 13. Oral Oncol. 2021. PMID: 33725617
2,076 results