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Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles.
Aschman T, Wyler E, Baum O, Hentschel A, Rust R, Legler F, Preusse C, Meyer-Arndt L, Büttnerova I, Förster A, Cengiz D, Alves LGT, Schneider J, Kedor C, Bellmann-Strobl J, Sanchin A, Goebel HH, Landthaler M, Corman V, Roos A, Heppner FL, Radbruch H, Paul F, Scheibenbogen C, Dengler NF, Stenzel W. Aschman T, et al. Among authors: landthaler m. Acta Neuropathol Commun. 2023 Dec 8;11(1):193. doi: 10.1186/s40478-023-01662-2. Acta Neuropathol Commun. 2023. PMID: 38066589 Free PMC article.
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.
Schulte-Schrepping J, Reusch N, Paclik D, Baßler K, Schlickeiser S, Zhang B, Krämer B, Krammer T, Brumhard S, Bonaguro L, De Domenico E, Wendisch D, Grasshoff M, Kapellos TS, Beckstette M, Pecht T, Saglam A, Dietrich O, Mei HE, Schulz AR, Conrad C, Kunkel D, Vafadarnejad E, Xu CJ, Horne A, Herbert M, Drews A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, Müller-Redetzky H, Heim KM, Machleidt F, Uhrig A, Bosquillon de Jarcy L, Jürgens L, Stegemann M, Glösenkamp CR, Volk HD, Goffinet C, Landthaler M, Wyler E, Georg P, Schneider M, Dang-Heine C, Neuwinger N, Kappert K, Tauber R, Corman V, Raabe J, Kaiser KM, Vinh MT, Rieke G, Meisel C, Ulas T, Becker M, Geffers R, Witzenrath M, Drosten C, Suttorp N, von Kalle C, Kurth F, Händler K, Schultze JL, Aschenbrenner AC, Li Y, Nattermann J, Sawitzki B, Saliba AE, Sander LE; Deutsche COVID-19 OMICS Initiative (DeCOI). Schulte-Schrepping J, et al. Among authors: landthaler m. Cell. 2020 Sep 17;182(6):1419-1440.e23. doi: 10.1016/j.cell.2020.08.001. Epub 2020 Aug 5. Cell. 2020. PMID: 32810438 Free PMC article.
Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters.
Teixeira Alves LG, Baumgardt M, Langner C, Fischer M, Maria Adler J, Bushe J, Firsching TC, Mastrobuoni G, Grobe J, Hoenzke K, Kempa S, Gruber AD, Hocke AC, Trimpert J, Wyler E, Landthaler M. Teixeira Alves LG, et al. Among authors: landthaler m. BMJ Open Respir Res. 2024 Feb 29;11(1):e001762. doi: 10.1136/bmjresp-2023-001762. BMJ Open Respir Res. 2024. PMID: 38423952 Free PMC article.
Grainyhead-like 2 Deficiency and Kidney Cyst Growth in a Mouse Model.
Yurtdas ZY, Kilic E, Boor P, Wyler E, Landthaler M, Jung K, Schmidt-Ott KM. Yurtdas ZY, et al. Among authors: landthaler m. J Am Soc Nephrol. 2024 Apr 24. doi: 10.1681/ASN.0000000000000353. Online ahead of print. J Am Soc Nephrol. 2024. PMID: 38656794
Despite the odds: formation of the SARS-CoV-2 methylation complex.
Matsuda A, Plewka J, Rawski M, Mourão A, Zajko W, Siebenmorgen T, Kresik L, Lis K, Jones AN, Pachota M, Karim A, Hartman K, Nirwal S, Sonani R, Chykunova Y, Minia I, Mak P, Landthaler M, Nowotny M, Dubin G, Sattler M, Suder P, Popowicz GM, Pyrć K, Czarna A. Matsuda A, et al. Among authors: landthaler m. Nucleic Acids Res. 2024 Mar 18:gkae165. doi: 10.1093/nar/gkae165. Online ahead of print. Nucleic Acids Res. 2024. PMID: 38499483
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
Trepte P, Secker C, Olivet J, Blavier J, Kostova S, Maseko SB, Minia I, Silva Ramos E, Cassonnet P, Golusik S, Zenkner M, Beetz S, Liebich MJ, Scharek N, Schütz A, Sperling M, Lisurek M, Wang Y, Spirohn K, Hao T, Calderwood MA, Hill DE, Landthaler M, Choi SG, Twizere JC, Vidal M, Wanker EE. Trepte P, et al. Among authors: landthaler m. Mol Syst Biol. 2024 Apr;20(4):428-457. doi: 10.1038/s44320-024-00019-8. Epub 2024 Mar 11. Mol Syst Biol. 2024. PMID: 38467836 Free PMC article.
Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.
Radke J, Meinhardt J, Aschman T, Chua RL, Farztdinov V, Lukassen S, Ten FW, Friebel E, Ishaque N, Franz J, Huhle VH, Mothes R, Peters K, Thomas C, Schneeberger S, Schumann E, Kawelke L, Jünger J, Horst V, Streit S, von Manitius R, Körtvélyessy P, Vielhaber S, Reinhold D, Hauser AE, Osterloh A, Enghard P, Ihlow J, Elezkurtaj S, Horst D, Kurth F, Müller MA, Gassen NC, Melchert J, Jechow K, Timmermann B, Fernandez-Zapata C, Böttcher C, Stenzel W, Krüger E, Landthaler M, Wyler E, Corman V, Stadelmann C, Ralser M, Eils R, Heppner FL, Mülleder M, Conrad C, Radbruch H. Radke J, et al. Among authors: landthaler m. Nat Neurosci. 2024 Mar;27(3):409-420. doi: 10.1038/s41593-024-01573-y. Epub 2024 Feb 16. Nat Neurosci. 2024. PMID: 38366144
Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.
Sun G, Kropp KA, Kirchner M, Plückebaum N, Selich A, Serrero M, Dhingra A, Cabrera JR, Ritter B, Bauerfeind R, Wyler E, Landthaler M, Schambach A, Sodeik B, Mertins P, Viejo-Borbolla A. Sun G, et al. Among authors: landthaler m. mBio. 2024 Feb 14;15(2):e0330823. doi: 10.1128/mbio.03308-23. Epub 2024 Jan 26. mBio. 2024. PMID: 38275838 Free PMC article.
Herpesviruses mimic zygotic genome activation to promote viral replication.
Full F, Walter S, Neugebauer E, Tan J, Drayman N, Franke V, Tay S, Landthaler M, Akalin A, Ensser A, Wyler E. Full F, et al. Among authors: landthaler m. Res Sq [Preprint]. 2023 Dec 13:rs.3.rs-3125635. doi: 10.21203/rs.3.rs-3125635/v1. Res Sq. 2023. PMID: 38168299 Free PMC article. Preprint.
742 results