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Inactivation of the Pyrimidine Biosynthesis pyrD Gene Negatively Affects Biofilm Formation and Virulence Determinants in the Crohn's Disease-Associated Adherent Invasive Escherichia coli LF82 Strain.
Rossi E, Leccese G, Baldelli V, Bibi A, Scalone E, Camilloni C, Paroni M, Landini P. Rossi E, et al. Among authors: landini p. Microorganisms. 2022 Feb 28;10(3):537. doi: 10.3390/microorganisms10030537. Microorganisms. 2022. PMID: 35336113 Free PMC article.
The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability.
Antoniani D, Rossi E, Rinaldo S, Bocci P, Lolicato M, Paiardini A, Raffaelli N, Cutruzzolà F, Landini P. Antoniani D, et al. Among authors: landini p. Appl Microbiol Biotechnol. 2013 Aug;97(16):7325-36. doi: 10.1007/s00253-013-4875-0. Epub 2013 Apr 14. Appl Microbiol Biotechnol. 2013. PMID: 23584245
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