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Legacy data sharing to improve drug safety assessment: the eTOX project.
Sanz F, Pognan F, Steger-Hartmann T, Díaz C; eTOX; Cases M, Pastor M, Marc P, Wichard J, Briggs K, Watson DK, Kleinöder T, Yang C, Amberg A, Beaumont M, Brookes AJ, Brunak S, Cronin MTD, Ecker GF, Escher S, Greene N, Guzmán A, Hersey A, Jacques P, Lammens L, Mestres J, Muster W, Northeved H, Pinches M, Saiz J, Sajot N, Valencia A, van der Lei J, Vermeulen NPE, Vock E, Wolber G, Zamora I. Sanz F, et al. Among authors: lammens l. Nat Rev Drug Discov. 2017 Dec;16(12):811-812. doi: 10.1038/nrd.2017.177. Epub 2017 Oct 13. Nat Rev Drug Discov. 2017. PMID: 29026211 Free article.
Optimising the design of preliminary toxicity studies for pharmaceutical safety testing in the dog.
Smith D, Combes R, Depelchin O, Jacobsen SD, Hack R, Luft J, Lammens L, von Landenberg F, Phillips B, Pfister R, Rabemampianina Y, Sparrow S, Stark C, Stephan-Gueldner M. Smith D, et al. Among authors: lammens l. Regul Toxicol Pharmacol. 2005 Mar;41(2):95-101. doi: 10.1016/j.yrtph.2004.10.006. Epub 2004 Dec 19. Regul Toxicol Pharmacol. 2005. PMID: 15698532
Preclinical toxicity and pharmacokinetics of a new orally bioavailable flubendazole formulation and the impact for clinical trials and risk/benefit to patients.
Lachau-Durand S, Lammens L, van der Leede BJ, Van Gompel J, Bailey G, Engelen M, Lampo A. Lachau-Durand S, et al. Among authors: lammens l. PLoS Negl Trop Dis. 2019 Jan 16;13(1):e0007026. doi: 10.1371/journal.pntd.0007026. eCollection 2019 Jan. PLoS Negl Trop Dis. 2019. PMID: 30650076 Free PMC article.
Real life juvenile toxicity case studies: the good, the bad and the ugly.
De Schaepdrijver L, Rouan MC, Raoof A, Bailey GP, De Zwart L, Monbaliu J, Coogan TP, Lammens L, Coussement W. De Schaepdrijver L, et al. Among authors: lammens l. Reprod Toxicol. 2008 Sep;26(1):54-5. doi: 10.1016/j.reprotox.2008.04.002. Epub 2008 Jun 2. Reprod Toxicol. 2008. PMID: 18514481
Phospholipidosis in rats treated with amiodarone: serum biochemistry and whole genome micro-array analysis supporting the lipid traffic jam hypothesis and the subsequent rise of the biomarker BMP.
Mesens N, Desmidt M, Verheyen GR, Starckx S, Damsch S, De Vries R, Verhemeldonck M, Van Gompel J, Lampo A, Lammens L. Mesens N, et al. Among authors: lammens l. Toxicol Pathol. 2012 Apr;40(3):491-503. doi: 10.1177/0192623311432290. Epub 2012 Jan 30. Toxicol Pathol. 2012. PMID: 22291062
Mouse organoids as an in vitro tool to study the in vivo intestinal response to cytotoxicants.
Jardi F, Kelly C, Teague C, Fowler-Williams H, Sevin DC, Rodrigues D, Jo H, Ferreira S, Herpers B, Van Heerden M, de Kok T, Pin C, Lynch A, Duckworth CA, De Jonghe S, Lammens L, Pritchard DM. Jardi F, et al. Among authors: lammens l. Arch Toxicol. 2023 Jan;97(1):235-254. doi: 10.1007/s00204-022-03374-3. Epub 2022 Oct 6. Arch Toxicol. 2023. PMID: 36203040
26 results